Inability To Metabolize Tamoxifen Changes Breast Cancer Outcomes

[News]

Breast cancer patients with a certain genetic liver enzyme alteration do not respond well to the hormone therapy tamoxifen as they have difficulty metabolizing the drug, leading to an increased risk of death and recurrence...

More... (http://www.medicalnewstoday.com/articles/254491.php)

[CarolineC]

I don't have time to post alot right now, but I am wondering if this has anything to do with Gilbert's Syndrome; are patients with this condition unable to metabolize Tamoxifen?

[karen z]

Interesting finding.