Manipulating transcription factor can change subtype of breast cancer

[News]

Australian scientists have shown how a 'transcription factor' causes breast cancer to develop an aggressive subtype that lacks sensitivity to oestrogen and does not respond to anti-oestrogen therapies such as Tamoxifen and aromatase inhibitors.

More... (http://www.news-medical.net/news/20121228/Manipulating-transcription-factor-can-change-subtype-of-breast-cancer.aspx)