NOTCH1 signaling promotes T-cell acute lymphoblastic leukemia-initiating cell regener

[News]

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.

More... (http://www.news-medical.net/news/20120703/NOTCH1-signaling-promotes-T-cell-acute-lymphoblastic-leukemia-initiating-cell-regeneration.aspx)