Finally! Shrinkage!

[chrisy]

Haven't seen the report, not even sure it's final, but I got a phone call last night with the GOODNEWS that the chemo/akt/herceptin regimen I'm on - which has been kicking my butt - is also kicking cancer butt! Maybe back to where I was about the end of October 11.

This is the first time in over a year that we've gotten "good" news about a scan. No wonder my hubby is a basket case!

Welcome back, Costanza!

and yes, God is good, all the time.

[dawny]

Woo-Hoo Chrisy, fantastic news - you go kick its butt!

Dawn

[ElaineM]

I am doing the "Happy Dance" for you !!!!!!!
I am happy for you.

[Mandamoo]

Yippee to our pioneer!
Such wonderful news.

[Gerri]

So happy for you Chrisy! Yay for shrinkage!! Love the Seinfeld reference - George has nothing on you! Hope you and your hubby can breathe a little easier do some celebrating this weekend.

[StephN]

Way TO GO! That downstream inhibitor seems to be having the right effect, along with the Taxol and Vitamin H.

In my case, it was a 3 drug approach that put me to NED. So, it seems to make a lot of sense to me.

Keep up the good work and maybe they will let you drop the kick-ass Taxol soon.

[Paty]

Chrisy,

I am soooooo happy for you!!!! God bless you and keep up the fight.

[Bunty]

Great news Chrissy!! You and your hubby must be thrilled.
Cheers Marie

[Redwolf8812]

I'm so happy for you!

[NEDenise]

Yay, Chris! You just made my day!
Here's a toast to MANY more good scans in your future!!
(Does a coffee toast count? It's 8 o'clock in the morning here.)

Sending a GIANT cross country hug to you!
Denise

[caya]

Great news Chrisy!! We LOVE shrinkage, even if George and co. didn't...

all the best
caya

[schoolteacher]

Chrisy, glad to hear your good news. God is good.

Amelia

[PinkGirl]

They shrink????

[allielala]

l am an new member but couldn't help but say l am so happy for you. l hope the weather on the weekend spoils you! :) l live in Brisbane Australia.

[MJsHusband]

Congratulations Chrisy!

[Debbie L.]

SO glad to hear your news, Chris. I've been noticing how quiet you've been and each day, hoping to see something from you.

I wish that it was only the cancer suffering, and not you too -- to achieve these results! But still, wonderful news.

When you feel up to it, maybe you'll tell us what the side effects are like, and how you'd compare them to other combos you've done. How others in the trial are faring, gossip like that?

Lots of love and good thoughts,
Debbie Laxague

[Del]

Congratulations! Wonderful news! As I look at your signature it appears that I am following closely in your treatment/response times. You have probably outlined this before, but can you remind me what the AKT trial is? I'm currently still responding to TDM1, but just wanted to check out future options.

[Kim in DC]

Yeah Chrissy!

[radiant]

Fantastic News Chrissy. Is this a hard
combo?

Kim

[chrisy]

Del,
The akt trial I am in as a phase I study of an akt pathway inhibitor ( a growth pathway that is "downstream" from the Her2 pathway) plus taxol plus (if you are her2+), Herceptin. Although the study I'm in is a dose escalation study, they are already at the maximum tolerated dose and just expanding people in at that level.

The akt agent is a drug called MK2206 and is an oral medication. It has been in various early phase trials for a little while in several types off cancer, including breast.

[chrisy]

Debbie L -I have been very quiet on the boards lately, mostly due to lack of time and energy what with "learning" the side effects on this trial, sneaking in a little bit of work, hassling with insurance companies (they didnt know who they were dealing with), multiple trips up to UcSF - sometimes up to 4 times a week - and oh yeah, tearing a muscle in my calf which is taking forever to heal!

Waah waah waah!

But I do have some trial gossip to pass along, and will do so soon , probably in the clinical trials thread.

[Joan M]

Chrisy, Fabulous news!!! Joan

[Becky]

Pioneer woman! I am very happy with your recent results, especially since it has been hard on you. Thrilling news! Many hugs, thoughts and best wishes from your friend on the right coast:)

[michka]

Chrisy, I am really happy. I was hoping so much you would have good results on this new trial and seeing your post just brings a big smile on my face. I hope the SEs are not too difficult. Michka

[fullofbeans]

Chrisy am so please for you, So glad that the combo is working for you..sorry one of my past mail had not udertstood that you were on Tax + H thought just the inhibitor. Glad you getting smacking results Go cheery Chrisy!!!!

[karen z]

Wonderful wonderful news Chris.
Really great to hear about this!!!!!!

[rhondalea]

I'm thrilled to hear this, Chris, although I wish you weren't having side effects. I'll be thinking happy, healing thoughts in your direction and laughing quietly at the insurance companies for being so silly as to think they could mess with you.

<happy dance>

[LittleJoanne]

Hello Chrisy, I'm new here and just wanted to say congratulations on the great news!

[Lien]

Wow! Doing my Happy Dutch Clogdance just for you. This is great news indeed. I'm so happy for you!

Jacqueline

[mmoons]

Chrisy-

Yeah, YEAH, YEAH!!!!!!

I don't post much but always lift you in prayer, along with our whole HER2 family. Praise God....such good news. Second only to your upcoming post about being NED.

So happy for your news!!!!!

Maureen

[jml]

Yaaaaaay, Chrissy!

Keeping the Faith with news like this:)

Jml

[Cannon]

That is great news, Chrisy. So glad to hear it! Keep up the good work.

[KDR]

Way to go, Chrisy, way to go! I am SOOO happy for you. Leading the way again, see...!
Love you
Karen

[DeenaH]

That is fantastic news!! Congratulations!!

[KsGal]

Go, Chrisy, Go!!!! May God continue to bless you.

[Pray]

How wonderful for You!!!!

[sassy]

YEA!!!! Constanza, shrinkage is good!

Would you like a little mole sauce with that shrinkage?

So glad to hear good news for you. Never doubted you'd be a butt kicker again! Keep it up!

[Laurel]

So doggoned happy to hear your stellar news, Chrisy-girl! I wish you were not getting knocked back by that combo, but I am so relieved to find it is working.

[Mary Anne in TX]

Chris, it's so good to hear good news for you. I'll search for the gossip in the trial section. Love some good scoop!

[Mary Jo]

One word sums up my feelings - HAPPY!

Mary Jo

[pibikay]

Good news inded Chrisy

[Lori R]

Chrisy,
Your posts are always entertaining, and the good news is an fantastic Bonus.

You are so brave and such a trail blazer for all of us.

I am so, so happy for you that the risks you are taking are paying off!!

Glad to see you back on the board!!!

Lori

[Jean]

Chrisy,
You made my weekend.
I am happy to hear your wonderful news.

hugs,
Jean

[Mtngrl]

Chrisy,

I'm so happy for you! Thank you for letting us know.

All the best,

[alicem]

Fantabulous news!! Woohoo!!!

[Adriana Mangus]

Dear Chrisy,

Happy to hear you are doing great!!

Now, Go and Celebrate.

Love,

Adriana

[Jean]

Chrisy,
You have waited a long time and now the bad spell is broken...so happy to hear your news.

hugs,
Jean