continuing herceptin, adding lapatinib increases overall survival w her2+ brain mets

[Lani]

by about 400% compared to treatment with radiation alone and just the act of adding lapatinib to herceptin increases OS by almost 100%

caveat:retrospecitive study from one institution

iopen access:

http://www.nature.com/bjc/journal/v106/n1/pdf/bjc2011531a.pdf

[hutchibk]

Very interesting. Even w/ caveat. Thanks Lani...

[karen z]

Thanks for posting.
k

[KsGal]

That is very interesting. Thanks so much for posting it.

[DeenaH]

Thanks as always, Lani! I truly believe Tykerb has been protecting my brain. This data makes that very likely.

[Joan M]

Thanks, Lani. Joan

[jml]

Haven't read the study yet, but wondering...
I had Tykerb in 6/09, was NED in brain at the time, but the Tykerb failed to control the disease in my body.
I wonder if it would be beneficial now, with the 8 spots that we've just discovered in my brain?