Tykerb/xeloda

[dawn]

Progression on abraxane, now on to tykerb/xeloda combo. I will stop herceptin and abraxane but continue on aredia. I'm a little anxious about stopping herceptin. Any thoughts or ideas on this.

Thanks

Dawn

[hutchibk]

Stopping Herceptin for Ty/Xel doesn't mean you're stopping Herceptin forever... I was on Herceptin for about 2 years when we switched to Ty/Xel (for brain mets)... it worked great for me for 18 months, and when we saw small progression we dropped the Xeloda and added in Herceptin, then I got another 2+ years on Ty/Herc... now I am in TDM1 trial which is also Herceptin based. You are probably far from being done w/ Herceptin, so don't worry too much.

[Trish]

Hi Dawn
I also had progression on Abraxane and now I am on Tykerb/Xeloda AND Herceptin. I have been on all three before but am hoping the three in combination will improve the situation till the next drug comes along. Bring on the Pertuzumab and/or TDM-1! As Brenda said you can resume Herceptin if need be but hopefully Xeloda/Tykerb will be enough for now. It certainly gave me a good year of tumour reduction. Remember Tykerb is targeting the HER2 receptors although differently to Herceptin.
All the best
Trish

[dawn]

Thanks Ladies,

will speak to my onc about herceptin, feeling better about the combo now. Anyone know anything on the TDM1 trails and whats happening. Sounds very promising.

Dawn

[schoolteacher]

Brenda,

Thanks for letting us know how long you tookTykerb and Herceptin. I am back on Herceptin after being off a year. I am currently taking only Herceptin and Tykerb.

Amelia