Herceptin Trastuzumab intrathecal

[alocin]

Dear all,
I try to find out which clinic is applying the Herceptin/ Trastuzumab intrathecal-method. Please, if somebody of you knows something, please let me know. I am asking for my best friend who is suffering from breast cancer HER 2 with brain metastases.
Thank you very much
Nicola

[schoonder]

Nicola, I know very little about this subject, but maybe more knowledgeable help will check in.
A clinical trial dealing with trastuzumab intrathecal which isn't recruiting as yet is listed on clinicaltrials.gov. No mention is made of brain metastasis but surely people at NorthWestern U might be able to provide further assistance. Most likely you'll need to locate an oncologist who's willing to use Herceptin off-label. Goodluck in finding help for your dear friend.
http://www.clinicaltrials.gov/ct2/show/NCT01325207?term=intrathecal+trastuzumab&rank=1

[krisvell]

Nicola,
There are so many knowledgeable people on this web site that can be of help. I think you would get more meaningful information if you could share a summary of your friend's Breast Cancer similar to the signatures you see on the posts.

I too have a single brian met and have thought about intratecal treatment too.

Kris....

[alocin]

Thank you very very much. I will write a signature as you mentionned. Where do you want to ask for this kind of therapy? I wish you all the best for you.

[Unregistered]

My wife started intrathecal herceptin in Chicago on Aug 1, 2011. We have done 2 treatments so far. We are the first in this trial. Those women with LM disease need to enroll in this trial. It can be found on the government web site or you can contact Dr. Raizer at Northwestern University in Chicago. My wife can be reached at cotyav54@yahoo.com

[Unregistered]

Thank you very much for your kind reply, I will tell my friend. All the best for your wife and for you. Thank you.

[Jackie07]

We do have at least one member who has undergone the Intrathecal procedure:

http://her2support.org/vbulletin/showthread.php?p=249680&highlight=Trastuzumab+intrathecal#post249680

[CourtneyL]

Hmmm, don't know how I missed this thread. Sorry for not chiming in sooner. Yes, I have been receiving Intrathecal Herceptin since April of this year. I go for a follow-up brain MRI tomorrow to see how things are going. I'll report back as soon as I know the results - hopefully things are still under control. I had a follow-up MRI after only two treatments in May of this year and it showed shrinkage to all four of my active brain mets. All the others that had been treated with Gamma Knife were either still shrinking or gone completely. Let's hope our magic Vitamin H can do the same!

[schoolteacher]

Courtney,

Hope to hear from you soon.

Amelia