AlaskaAngel
08-24-2010, 01:30 PM
The numbers given in some current clinical trial descriptions describe us at this point in time, and I think they are interesting and helpful enough to share them:
"The purpose of the investigators study is to examine the effects of resistance training with and without nutritional supplementation and weight loss on the reasons (mechanisms) underlying the development of metabolic syndrome (high blood pressure, cholesterol, diabetes, body weight/obesity), muscle weakness and wasting (sarcopenia), impaired physical (poor balance and walking) and cognitive function associated with breast cancer survivorship. Breast cancer is the most frequently diagnosed cancer in women, representing 26% of all female cancers. It is also the second leading cause of cancer related deaths in the US for women. Chemotherapy and treatment related menopause from hormonal therapy is associated with an increase in body weight in 60% of women diagnosed with breast cancer. Observational studies have shown a 30% increase in mortality rates from adiposity following breast cancer. Survivors with high body mass index (BMI) have double the risk of recurrence and a 60% increase in risk of death when compared to women with a normal weight. Additionally, side effects of the cancer and treatment therapies may result in inadequate intakes of various nutrients, including protein and vitamin D, associated with cardiovascular disease (CVD) and type 2 diabetes. High concentrations of systemic and local inflammation correlate well with CVD and diabetes risk. There is substantial evidence to support that incorporating physical activity and weight management into one's lifestyle can reduce inflammation and, ultimately, the progression to CVD and diabetes. Understanding the role of exercise and diet management in the health of breast cancer survivors will allow us to translate these findings into therapy guidelines."
From:
Clinical trials identifier: NCT01151488
From 2008:
"Women aged 50 and older are disproportionately affected by breast cancer, not only in terms of new diagnoses, but also in terms of survivorship. Approximately 85% of women who receive a first diagnosis of breast cancer are aged 50 and over, thus older women constitute the largest group of breast cancer survivors. "
Clinical trials identifier: NCT00591747
- AlaskaAngel
"The purpose of the investigators study is to examine the effects of resistance training with and without nutritional supplementation and weight loss on the reasons (mechanisms) underlying the development of metabolic syndrome (high blood pressure, cholesterol, diabetes, body weight/obesity), muscle weakness and wasting (sarcopenia), impaired physical (poor balance and walking) and cognitive function associated with breast cancer survivorship. Breast cancer is the most frequently diagnosed cancer in women, representing 26% of all female cancers. It is also the second leading cause of cancer related deaths in the US for women. Chemotherapy and treatment related menopause from hormonal therapy is associated with an increase in body weight in 60% of women diagnosed with breast cancer. Observational studies have shown a 30% increase in mortality rates from adiposity following breast cancer. Survivors with high body mass index (BMI) have double the risk of recurrence and a 60% increase in risk of death when compared to women with a normal weight. Additionally, side effects of the cancer and treatment therapies may result in inadequate intakes of various nutrients, including protein and vitamin D, associated with cardiovascular disease (CVD) and type 2 diabetes. High concentrations of systemic and local inflammation correlate well with CVD and diabetes risk. There is substantial evidence to support that incorporating physical activity and weight management into one's lifestyle can reduce inflammation and, ultimately, the progression to CVD and diabetes. Understanding the role of exercise and diet management in the health of breast cancer survivors will allow us to translate these findings into therapy guidelines."
From:
Clinical trials identifier: NCT01151488
From 2008:
"Women aged 50 and older are disproportionately affected by breast cancer, not only in terms of new diagnoses, but also in terms of survivorship. Approximately 85% of women who receive a first diagnosis of breast cancer are aged 50 and over, thus older women constitute the largest group of breast cancer survivors. "
Clinical trials identifier: NCT00591747
- AlaskaAngel