Noni Juice

[dawn]

Does anyone know anything about Noni Juice. I met someone yesterday that was dx with liver cancer and even though he did the treatment, he credits noni juice with getting rid of his lesions. I didn't get into why, or how of it. He just seemed so sincere and sure that this juice worked. Apparently it helps the liver function better and cleans out all the toxins. "Try it Try it, it will make a difference. Any imput ladies?

DAwn

[v-ness]

hi dawn- don't know anything from personal experience, except that i choked at the price when i googled it. knew one person who drank it religiously. he had an aggressive brain tumor and needless to say it did not save him. valerie

[Becky]

Maybe noni juice doesn't cross the blood brain barrier:) lol

[Rich66]

Been following supps to a degree and don't see much on El Noni. I would reach for green tea (http://her2support.org/vbulletin/showthread.php?t=44079) and the milkable thistle (http://her2support.org/vbulletin/showthread.php?p=218176#post218176) first. But who knows...some mice liked it.


Phytother Res. (javascript:AL_get(this,%20'jour',%20'Phytother%20 Res.');) 2003 Dec;17(10):1158-64.
Antitumour potential of a polysaccharide-rich substance from the fruit juice of Morinda citrifolia (Noni) on sarcoma 180 ascites tumour in mice.

Furusawa E (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Furusawa%20E%22%5BAuthor%5D), Hirazumi A (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Hirazumi%20A%22%5BAuthor%5D), Story S (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Story%20S%22%5BAuthor%5D), Jensen J (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Jensen%20J%22%5BAuthor%5D).
Department of Pharmacology, John Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
An immunomodulatory polysaccharide-rich substance (Noni-ppt) from the fruit juice of Morinda citrifolia has been found to possess both prophylactic and therapeutic potentials against the immunomodulator sensitive Sarcoma 180 tumour system. The antitumour activity of Noni-ppt produced a cure rate of 25%-45% in allogeneic mice and its activity was completely abolished by the concomitant administration of specific inhibitors of macrophages (2-chloroadenosine), T cells (cyclosporine) or natural killer (NK) cells (anti-asialo GM1 antibody). Noni-ppt showed synergistic or additive beneficial effects when combined with a broad spectrum of chemotherapeutic drugs, including cisplatin, adriamycin, mitomycin-C, bleomycin, etoposide, 5- fl uorouracil, vincristine or camptothecin. It was not beneficial when combined with paclitaxel, cytosine arabinoside, or immunosuppressive anticancer drugs such as cyclophosphamide, methotrexate or 6-thioguanine. Noni-ppt also demonstrated beneficial effects when combined with the Th1 cytokine, interferon gamma, but its activity was abolished when combined with Th2 cytokines, interleukin-4 or interleukin-10, thereby suggesting that Noni-ppt induces a Th1 dominant immune status in vivo. The combination of Noni-ppt with imexon, a synthetic immunomodulator, also demonstrated beneficial effects, but not when combined with the MVE-2 copolymer, a high molecular weight immunomodulator. It was also not effective when combined with interleukin-2 or interleukin-12. Copyright 2003 John Wiley & Sons, Ltd.

PMID: 14669249 [PubMed - indexed for MEDLINE]

[dawn]

Thank you Rich,

Does milk thistle interact with any medications? or should any herbals be discussed with the onc first

[Rich66]

Hard to say about posible negative interactions. I haven't seen any noted..doesn't mean they don't exist. But then..you could say the same thing about any number of conventional medicine combinations. The recent chemo/thistle study seems comforting. It would seem prudent to share the compiled info with your onc first. You've got Steph N as a case study mega success.