her2+ brst cancer, Grade III associated with nulliparity, late age at 1st childbirth

[Lani]

in Medscape From Reuters Health Information
Nulliparity, Late Age at First Childbirth Linked to Aggressive Breast Cancer




NEW YORK Oct 28 - Nulliparity and late-life first childbirth are associated with more agresssive breast cancer, according to Swedish researchers.

"We found that nulliparous women had a statistically significant high risk of grade III and HER2 over-expressing tumors," Dr. Salma Butt, of Malmo University Hospital, Sweden, and colleagues write in the October 15th issue of the International Journal of Cancer.

[Chelee]

Interesting. I have no family history of cancer on either side of the family. I'm the only one that ended up with bc...or any type of cancer for that matter. I stepped into a pre-made family and never had any bio childern...just my two step-kids I raised. So yet another possible reason for having Her2 bc.

Chelee

[Jackie07]

I had tried three infertility treatments and all I got were three uterine fibroids. I think it was some genetic malfunction that caused my brain tumor, infertility, and breast cancer. Chinese has an old saying, "born in the wrong hour." I was born almost two months premature, definitely in the very 'wrong' hour.

Nulliparity and late child birth have all been said to be related to breast cancer. I wonder how they got narrowed down to be related to just the Her2+ Grade III subtype?

[bejuce]

Well, I have 3 kids (first one at 31). Breastfed them all until they were 2 years old and ended up with a very aggressive HER-2+ tumor at 38. I've met other young moms in a similar situation. Not sure I buy it.

[Lien]

These are relative risks. My cancer was found in 2004. Had my kids in 1995 and 2000, breastfed for a year. I was an older mom, though. I was 40 when my youngest was born.

Jacqueline

[Chelee]

Jackie, That is a good question you asked? I wondered the same?

Chelee

[whatz]

I was 26/28 when my boys were born and breast fed both for a year. There is no cancer history in my family, I'm the first.

[sassy]

I was 31 when my first son was born. Second son 20 months later. Breastfed both. I am the first in my family on either side with breast cancer.