T-DM! Trial Update

[Joe]

A Study of Trastuzumab-MCC-DM1 (T-DM1) in Patients With HER2-Positive Locally Advanced or Metastatic Breast Cancer and the Safety and Tolerability of Combined T-DM1 and Pertuzumab in Patients With Early Disease Progression (http://clinicaltrials.gov/ct2/show/NCT00943670?term=NCT00943670&rank=1)
Genentrech has added additional sites to the above trial:
Locations:
United States, Illinois
Decatur Memorial Hosp & CCSCI
2300 North Edward Street
Decatur IL 62526USA

United States, Indiana
Horizon Onc Ctr-Lafayette
1345 Unity Place
Suite 345
Lafayette IN 47905 USA

United States, Maine
Maine Ctr for Cancer Medicine
100 Campus Drive
Unit 108
Scarborough ME 04074 USA

United States, Maryland
Annapolis Medical Specialists
900 Bestgate
Suite 300
Annapolis MD 21401 USA

United States, Missouri
Capitol Comprehensive CA Care
1241 West Stadium Blvd
Jefferson City MO 65109 USA


United States, Ohio
Mid Ohio Onc Hematology Inc
The Mark H. Zangmeister Center
3100 Plaza Properties Blvd.
Columbus OH 43219 USA


Regards
Joe

[StephN]

Joe -
Coeur d'Alene, Idaho is not listed. But I have a friend here who is nearly finished with the qualification process for that location.

She says she found it on the Clinicaltrials.gov site. The first treatment is with the T-DM1 only and if all is well the patient gets pertuzumab is given the next time.

[Pam P]

Sheila -- IL!!!! Can you qualify for this one???

[Joe]

Steph,
That is an additional study:

http://clinicaltrials.gov/ct2/show/NCT00943670?term=Coeur+d%27Alene%2C+Idaho+%2C+t-dm1&rank=1

Regards
Joe

[Carolyns]

Hi Joe,

The link that you posted at the top on your original post has the same site for treatment that Steph mentions. I think it is the same trial that I am trying to get in. I will call those other centers tomorrow to find out.

Thanks for everything.

Carolyn

[chrisy]

Sheila - I was thinking about that too! Reading the exclusions, it seems you would be able to qualify for this one.

Also, I encourage everyone to push on locations, the "listed locations" is never correct, it seems.

[Sheila]

Thanks Pam and Chrisy
I am going to call Decatur, just trying to remember if its weekly or every 3 weeks, as Decatur is at least a 3 hour trip for me....I am going to call tomorrow...today its off to Chicago to see the ortho for my Grandaughter, and get her next back surgery scheduled...only Jasmine owuld look forward to surgery!!! She was up at 5:30 anxious to go! Must be the handsome Dr she has...she is going to be 13 soon!!!!

[runtolive]

sheila...in previous tdm1 trials, 2 locations were near chicago. one maybe at northwestern..

[Sheila]

I did not qualify due to previous use of Xeloda, and the first time due to no previous anthracycline therapy

[Ellie F]

Hi Sheila
I am so sorry you do not qualify, it makes me so mad that there isn't one available yet. Surely Genentech must come up with one soon!
Love Ellie

[IRENE FROM TAMPA]

Hi Sheila

looking over your post I see that you are trying to get into the Her/DM1 trial and you mentioned that they excluded you at one point for use of Xeloda.

I had Xeloda a couple of years ago while on Tykerb and was still accepted. Now the trial of DM! I was on was every 3 weeks Phase II which has since closed. Maybe the one you tried had that as an exclusion. I know that my research co-ordinator fought very hard for me for other reason's at the time.

Good luck - it is a wonderful drug.