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View Full Version : UCLA's Jonsson Cancer Center Scientists Identify Signaling Pathway Driving A Deadly


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11-15-2008, 05:04 AM
An intra cellular pathway not previously linked to breast cancer is driving a sub-type of the disease that is highly lethal and disproportionately over-represented in African American women. The pathway regulates how cells identify and destroy proteins and represents a class of genes called proteasome targeting complexes. The work shows that basal cancer cells degrade the tumor suppressor gene p27 by making a new type of proteasome targeting complex.

More... (http://www.medicalnewstoday.com/articles/129544.php)