HER-2 and IGF-IR inhibitors synergize to combat breast cancer growth

[Hopeful]

Article: http://www.breastcancersource.com/breastcancersourcehcp/6096_33910_0_0_0.aspx?

Abstract: http://annonc.oxfordjournals.org/cgi/content/abstract/mdn406

Hopeful

[AlaskaAngel]

Thanks for this.

Maybe researchers could take this one step farther, and instead of using a IGF-IR antagonist they could figure out what causes the upregulation in the first place, and how to avoid it.

"They found IGF-IR expression was significantly upregulated in most breast cancer samples relative to the controls."

AlaskaAngel