Mjo

[Becky]

MJo

In answer to your question - if you don't do the trial you will be able to take an AI another 5 years. If your onc won't let you and you don't want to change onc's, then you are no better off than if you were in the control arm of the trial. However, you might find an onc who will let you stay on another 5 years. If you are in the trial and get on a control arm, you will have no choices to make. Why don't you ask your onc what his opinion of a second 5 yrs is and if he plans to keep you on something. If he says he is planning on it, then don't do the trial. You can then choose what you want to do then (as you don't have to stay on if you don't want to).

[nancy dip]

I have wondered about this. We all seem to be given the standard dose, no matter our body weight when other drugs are so carefully measured.
Also, no account is taken of our age at starting AIs ie 55 or65 which surely has an effect on our body's natural estrogen.
Personally, AIs have made me very stiff but I think its worth it to try to avoid the blip (?7yrs) of recurrences for ER+s
Nancy