Gene Causes Cancer to Metasthesize

[Joe]

http://news.yahoo.com/s/afp/20080313/ts_afp/healthdiseasecancerbiotechdrugs_080313084709

[Bubble]

Hi,
I read the same stuff in the local paper and then checked it on the net.
Its a big step....................
Love and luck to all
Bubble

[StephN]

From the article:

"But the SATB1 protein is just such a marker. A tumour in which it is activated "is destined to metastasise," said Kohwi-Shigematsu.
Metastasis is the overwhelming cause of death in patients with solid tumours. Less than 10 percent of women with metastatic breast cancer survive beyond a decade, and just over a quarter make it past five years."

We have long wondeded WHY some of us would do well after mets and some would continue to fight and fight. The article says it not yet known WHAT switches ON this protein, but at least the researchers are zeroing in, and I believe they will figure out how this marker works.

My question is how does this SATB1 marker interact with HER2??