Can herceptin be used for her2-??

[Rozebud]

Is there any evidence at all that herceptin can be used for those that are considered her2-? What about only weakly positive? If so, where is the cut-off? Just asking for a friend.....the theory is that we all have her2 genes, but wouldn't it work even if the overexpression was not as strong?

Any articles or studies?

TIA! You ladies ROCK!
Rose

[RhondaH]

I know they are studying where the "cutoff" should be. I know I am weakly positive 3.16 FSH and I had Herceptin. Here's an article and I will see if I can find any current studies. Take care and God bless.

Rhonda

http://www.nytimes.com/2007/06/12/health/12canc.html?ref=science

[fauxgypsy]

I put this link in my post 'new info on herceptin" It adresses your question. I tried to rename the post but couldn't.

http://www.nytimes.com/2007/06/12/health/12canc.html?_r=1&adxnnl=1&oref=slogin&ref=science&adxnnlx=1181777016-zK1xq/nDMrP6WGbWrQjucA

Leslie

[Rozebud]

Thank you! Exactly what I needed. I'm heading to ASCO's site now.