Herceptin-eventually stops working??

[Ceesun]

Greetings to All, In much of the literature I have read on herceptin it says it eventually stops working. Does anyone know how long it is effective??? Is there a predictable track record--is it long lasting for some of us? So glad tykerb is in the picture now, too. Any comments are appreciated. Happy Spring to All. Ceesun

[hutchibk]

My onc told me last month that he knows of a woman (not his patient) who has been on Herceptin for over 5 years and is still clear. He has also heard of women who have stayed on Herceptin since trials in 1997/98.

I wonder if the Herceptin just flat out stop working? Or does the Her2neu develop a resistance, like germs do to antibiotics?

[Bev]

Cee, Look up Gina Popp's and others posts. Under certain scenarios people can become resistant to H. I don't think any of this is proven w/o a doubt, You are at a point where you can look more deeply into studies and try to draw some conclusion. But we are probably are not there yet in concluding who wil be resistant. BB