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Joy
10-27-2006, 09:54 AM
Hi all, just wanted to let folks know that Navelbine appears to be working. I freaked out about the circulating tumor cell test result of 6 (5 or below is considered much better) when I began this tx and received a lot of support from people here about that. After 5 weeks on Navelbine (w/ herceptin) we repeated the circulating tumor cell test. The result was... 0...ta dah!!!! My liver enzymes (ALT/AST) had also begun to drop. Yesterday, I found out that my CA 27.29 went from 240 to 153 in a month and my ALT/AST are so close to normal. I also have to admit that I feel better than I did in many ways. I realize now that the liver tumors were causing me some discomfort-had a lot of denial there.

I've been reading more on here about herceptin side-effecty things and I'm wondering if just being on the stuff long term the way many of us have been makes things start to happen. I have ALWAYS been able to control my weight (grateful for that), but lately I've gained some in the middle and I KNOW I am not eating more than usual. I'm a vege-aholic, i don't like junk food, eat little meat, some cheese, blah, blah, blah. But my clothes are too tight in the waist now, I refuse to buy new ones. i have chronic sinus stuff and some of the digestive junk that people have mentioned.

I'm thinking that I am now resistant to herceptin anyway (maybe navelbine will spark the synergy). Going off of it and on to, say, Tykerb I guess will depend on how long I continue to improve. We are also not sure if I've lost hormonal pathways to treat-I hope not, but I know all of the cross-talk trickiness can happen. I'm excited to see all the good posts about rectifying resistances, though.

Anyway, I'm excited to have good news as this last year has been too much of a rollercoaster. I'm also excited to have hair-i look like an FBI agent, but I have hair! Eyebrows, too, and even better eyelashes than before-it's about time something came back improved! I also realize now how much taxol/carbo depressed me mentally, emotionally and physically. Navelbine has its stuff, but I am energetic enough (comparative value is a wonderful thing) to do more around the house. I'm back to teaching a parent/child class in my kids' school's early childhood program. Volunteering at school a bit more. Goofing off with my kids more. Helping friends out again feels so good after all they have done for me. I take my supplements more consistently. I started an awesome hypno/psychotherapy program. Getting better at meditating too. Saw Deepak Chopra in Denver this week and loved the lecture. His new book is Life After Death; the burden of proof. It so complemented the meditative/hypnotherapy work I've been doing and it all feels good. I just hope I can continue to think these things even when cancer stuff gets rough.

So more update than I planned on giving, but there it is. I am taking time everyday to hold ALL of us in a healing space. I root for everyone and have been saddened by recent losses and setbacks for people. My prayers are with everyone past and present.

chrisy
10-27-2006, 10:26 AM
I've been thinking about you a lot and was hoping you'd update with some good news! You've been in my thoughts and prayers. So I'm feelin' your name about your great news.

I'm so glad you not only have gotten great response to this new combo, but especially that you are feeling so much better. I hear you about the taxol/carbo depression - when I was getting that I'd get treated on Friday and by Monday at noon I'd be crying hysterically. Of course there are lots of legitimate emotions and fears we experience, but strong chemo definitely impacted my ability to cope.

So happy you are able to enjoy another slapdown. You didn't mention chocolate...maybe you should meditate on that, too!

love
Chris

mts
10-27-2006, 11:03 AM
Jump for Joy!

I am really happy for you ... congrats!

MTS (Maria)

Barbara H.
10-27-2006, 01:08 PM
Thank you for sharing your good news. I'm pleased to hear that you are also feeling better.
Barbara H.

lexigirl
10-27-2006, 02:07 PM
Yesss!!! That is great news!! I am so happy that you are feeling well and the navelbine is doing its job!

Hugs and Prayers,
Lexi

Vanessa
10-27-2006, 03:28 PM
I join the others in congratulating you on your good news. Thanks for keeping up in your thoughts and keep up the good work. I hope your new drug combination works really well for you.

SusanV
10-27-2006, 03:29 PM
Joy,

Just wanted to say that I am so very happy for you, that things are looking up ! We all deserve a reprieve from all the gloom & doom that we can feel during our journeys with this dreadfull disease. I feel happy just reading about your happiness ! Thanks for sharing

suzan w
10-27-2006, 04:01 PM
You GO girl!!! Great news!!!

tousled1
10-27-2006, 06:27 PM
So happy to hear that the Naveline seems to be working. Treat yourself -- you certainly deserve it!

Yorkiegirl
10-27-2006, 07:33 PM
Joy this is such WONDERFUL news. I am so glad that you are feeling so much better.


You will remain in my prayers.

Sending ((((((HUG'S))))

Tom
10-27-2006, 07:40 PM
What else can I say Joy? Fabulous news. I couldn't be happier for you. And thank you for worrying about the rest of us too.

Sincerely,
Tom

Liz J.
10-27-2006, 07:47 PM
Hi Joy,

God Bless on the good news. This is an inspiration for us all.

Sincerely,

Liz J.

Bev
10-27-2006, 07:48 PM
I'm glad things are working out. Take it as the gift it is,I hope all your new news is great. BB

lindaw
10-28-2006, 12:27 AM
Great news Joy. Its so nice when a chemo works - all the best.


love
lindaw

Julie2
10-28-2006, 04:10 AM
great news Joy, I am so happy for you

Julie

eric
10-28-2006, 05:17 AM
0, doesn't get any better than that. You go girl! Eric

karen raines hunt
10-29-2006, 01:45 PM
Dear Joy,

Thanks for sharing the great news!!!

Karen Hunt

Joy
10-29-2006, 03:09 PM
Thanks everyone, I can hear your cheers and it feels great!

StephN
10-29-2006, 07:32 PM
Navelbine has been a good drug for a number of us on this board. It did in my extensive liver mets, in combination with Taxol and Herceptin. As has often been said here, for many of us the Herceptin needs another drug to boost its efficacy, and this is the key to pushing back the cancer.

As the others have said, I repeat how happy I am for your recent success.
Stay with the program until you are NED. OK?

Vicki
10-29-2006, 10:25 PM
Joy,

What great news that your test results are going in the best direction possible. Keep up the good work you're doing in all areas, from the medical to the family and social connections you've got going again. The meditation is an excellent way to calm things in our lives. I saw Deepak Chopra on television talking about his book; I'm sure it's a good one, but I haven't read it yet. Thanks for filling us in on everything. Keep living well.

Vicki Z

Lolly
10-30-2006, 07:50 AM
Joy, I'm so glad for you! What a wonderful feeling when you see results. Navelbine worked very well for me for 5 years...I was on it intermittenly during that time, with Herceptin, and had great results. Thanks for sharing the good news, and keep it coming:)

<3 Lolly

karenann
10-30-2006, 08:49 AM
What wonderful news.

Hugs,
Karen

rinaina
10-30-2006, 01:23 PM
Great news Joy and thanks for sharing everything. We need to hear the good news to balance all the bad news we hear. Hoping all continues on this positive track for you.

Jean
10-30-2006, 05:27 PM
Dear Joy,
I was so happy to read your post....
I wish you continued success with your treatments.
God Bless.

Jean