judiek
09-19-2005, 05:52 PM
Good Evening,
Just wondering if anyone know anything about this clinical trial. I was on the avastin and taxol clinical trial for 15 months. I had minor progression then went to arimidex...it's not working. I have lots of progression and need to do another chemo. Xeloda is the next drug choice and now were trying to do it with another drug. This trial is being done at many locations and just wondering if anyone has any info...thanks for any input. I do have an appt for Oct 3rd with new oncologist...my clinic doesn't have this trial. I hate having to wait two more weeks to see a doctor when this beast is growing and spreading...but hate to loose out on possible benefits from the experimental drug TIPIFARNIB.
warmly,
judiek
History
Discovered lump Sept. 2002 (mammo didn’t pick it up).
Had 3 mammo’s in my 30's...not to sure mammo’s did me any good.
Dx Oct 2002-just turned 41.
IDC and pagets disease, stage 2B, grade 3/3, nottingham scale 9/9.
3cm, lumpectomy,clean margins.
er/pr-pos, her2 neg, 2/25 nodes w/cancer.
Nov 2002-March 2003-FEC (5fu, epirubicin, cytoxen).
March 2003- started tamoxifen.
May 2003- finished rads (33tx).
June 2003-CT/PET Scan- clear.
Started 3 month check ups w/lab.
July 2003-Lost my brother.
Dec 2003-complete hysterectomy/lost my father 4 days later.
Jan 2004-extensive mets, both lungs & liver, pleural effusion(labs normal)stopped tamoxifen .
Feb 2004- CEA-23 (0-3 normal) CA27.29-66.1 (0-38 normal).
Feb 23, 2004-CLINICAL TRIAL AVASTIN/TAXOL.
April 27th, 2005- CA27.29 is 23 /CEA 6.0...was.8 last August.
April 27th-DONE WITH AVASTIN/TAXOL...PROGRESSION.
15 months on trial which made my 5 lung nodules disappear/started with 9 liver nodules...now have 4 left -2 @9mm, 1@ 1cm, 1@ 1.5cm. Progression was small pleural effusion around lung, heart and some slightly enlarged nodes in chest and abdomen.
May, 20005-Started ARIMIDEX.
June 2, CEA up to 7.0 /CA27.29 down to 18.5 from 23.
June 28, CT stable CEA @6.9 / CA27.29 is 18.3
July 28, Ct stable (done because of increased cough) CEA 7.1 /CA27.29 18.8
Sept 14, Progression to lungs and liver again...CEA @10.2...looking for another trial
WE NEED A CURE
Just wondering if anyone know anything about this clinical trial. I was on the avastin and taxol clinical trial for 15 months. I had minor progression then went to arimidex...it's not working. I have lots of progression and need to do another chemo. Xeloda is the next drug choice and now were trying to do it with another drug. This trial is being done at many locations and just wondering if anyone has any info...thanks for any input. I do have an appt for Oct 3rd with new oncologist...my clinic doesn't have this trial. I hate having to wait two more weeks to see a doctor when this beast is growing and spreading...but hate to loose out on possible benefits from the experimental drug TIPIFARNIB.
warmly,
judiek
History
Discovered lump Sept. 2002 (mammo didn’t pick it up).
Had 3 mammo’s in my 30's...not to sure mammo’s did me any good.
Dx Oct 2002-just turned 41.
IDC and pagets disease, stage 2B, grade 3/3, nottingham scale 9/9.
3cm, lumpectomy,clean margins.
er/pr-pos, her2 neg, 2/25 nodes w/cancer.
Nov 2002-March 2003-FEC (5fu, epirubicin, cytoxen).
March 2003- started tamoxifen.
May 2003- finished rads (33tx).
June 2003-CT/PET Scan- clear.
Started 3 month check ups w/lab.
July 2003-Lost my brother.
Dec 2003-complete hysterectomy/lost my father 4 days later.
Jan 2004-extensive mets, both lungs & liver, pleural effusion(labs normal)stopped tamoxifen .
Feb 2004- CEA-23 (0-3 normal) CA27.29-66.1 (0-38 normal).
Feb 23, 2004-CLINICAL TRIAL AVASTIN/TAXOL.
April 27th, 2005- CA27.29 is 23 /CEA 6.0...was.8 last August.
April 27th-DONE WITH AVASTIN/TAXOL...PROGRESSION.
15 months on trial which made my 5 lung nodules disappear/started with 9 liver nodules...now have 4 left -2 @9mm, 1@ 1cm, 1@ 1.5cm. Progression was small pleural effusion around lung, heart and some slightly enlarged nodes in chest and abdomen.
May, 20005-Started ARIMIDEX.
June 2, CEA up to 7.0 /CA27.29 down to 18.5 from 23.
June 28, CT stable CEA @6.9 / CA27.29 is 18.3
July 28, Ct stable (done because of increased cough) CEA 7.1 /CA27.29 18.8
Sept 14, Progression to lungs and liver again...CEA @10.2...looking for another trial
WE NEED A CURE