sarcoma

[Cali]

i was wondering if anyone had any information or knew anything about high-grade peripheral nerve sheath sarcoma( with rahbomyoplastic and cartilegenous differentiation). it would be a big help. thanks.

[Lani]

Here is page one of twelve pages that come up when you put peripheral nerve sarcoma into
PubMED : (NUMBER SEVEN LOOKS TO BE RIGHT ON THE TARGET)
Items 1 - 20 of 237

PAGE 1 of 12
Next
1: Leow AM, Halim AS, Wan Z. Related Articles, Links
Free Full Text Reconstructive treatment following resection of high-grade soft-tissue sarcomas of the lower limb.
J Orthop Surg (Hong Kong). 2005 Apr;13(1):58-63.
PMID: 15872402 [PubMed - in process]
2: Shah H, Pervez S. Related Articles, Links
Abstract Immunophenotypic characterization of high grade pleomorphic sarcomas: a demographic and immunohistochemical study in a major referral center of Pakistan.
J Pak Med Assoc. 2005 Mar;55(3):101-4.
PMID: 15852744 [PubMed - in process]
3: Liang YM, Li XH, Lu YL, Zhong M. Related Articles, Links
Abstract [Morphology and immunohistochemical characteristics of hepatic primary and metastatic malignant spindle cell tumors]
Zhonghua Yi Xue Za Zhi. 2005 Jan 12;85(2):96-100. Chinese.
PMID: 15774214 [PubMed - in process]
4: Otsuka H, Graham MM, Kubo A, Nishitani H. Related Articles, Links
Abstract FDG-PET/CT findings of sarcomatous transformation in neurofibromatosis: a case report.
Ann Nucl Med. 2005 Feb;19(1):55-8.
PMID: 15770975 [PubMed - in process]
5: Santaella Y, Borrego I, Lopez J, Ortiz MJ, Vazquez R. Related Articles, Links
Abstract [18-FDG-PET in a case of recurrent malignant schwannoma]
Rev Esp Med Nucl. 2005 Mar-Apr;24(2):127-30. Spanish.
PMID: 15745683 [PubMed - in process]
6: Kim DH, Murovic JA, Tiel RL, Moes G, Kline DG. Related Articles, Links
Abstract A series of 146 peripheral non-neural sheath nerve tumors: 30-year experience at Louisiana State University Health Sciences Center.
J Neurosurg. 2005 Feb;102(2):256-66.
PMID: 15739553 [PubMed - indexed for MEDLINE]
7: Kim DH, Murovic JA, Tiel RL, Moes G, Kline DG. Related Articles, Links
Abstract A series of 397 peripheral neural sheath tumors: 30-year experience at Louisiana State University Health Sciences Center.
J Neurosurg. 2005 Feb;102(2):246-55.
PMID: 15739552 [PubMed - indexed for MEDLINE]
8: Pytel P, Taxy JB, Krausz T. Related Articles, Links
Abstract Divergent differentiation in malignant soft tissue neoplasms: the paradigm of liposarcoma and malignant peripheral nerve sheath tumor.
Int J Surg Pathol. 2005 Jan;13(1):19-28.
PMID: 15735851 [PubMed - in process]
9: Pabiszczak M, Wozniak A, Wierzbicka M, Leszczynska M, Szyfter W. Related Articles, Links
Abstract [Diagnostic difficulties in the laryngeal malignant peripheral nerve sheath tumor (MPNST)]
Otolaryngol Pol. 2004;58(6):1133-6. Polish.
PMID: 15732835 [PubMed - indexed for MEDLINE]
10: Sabah M, Cummins R, Leader M, Kay E. Related Articles, Links
Abstract Leiomyosarcoma and malignant fibrous histiocytoma share similar allelic imbalance pattern at 9p.
Virchows Arch. 2005 Mar;446(3):251-8. Epub 2005 Feb 25.
PMID: 15731925 [PubMed - in process]
11: Galanis E, Okuno SH, Nascimento AG, Lewis BD, Lee RA, Oliveira AM, Sloan JA, Atherton P, Edmonson JH, Erlichman C, Randlev B, Wang Q, Freeman S, Rubin J. Related Articles, Links
Abstract Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas.
Gene Ther. 2005 Mar;12(5):437-45.
PMID: 15647767 [PubMed - in process]
12: Joyner DE, Wade ML, Szabo A, Bastar J, Coffin CM, Albritton KH, Bernard PS, Randall RL. Related Articles, Links
Abstract Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivo.
J Cancer Res Clin Oncol. 2005 Mar;131(3):137-46. Epub 2004 Dec 22.
PMID: 15614524 [PubMed - indexed for MEDLINE]
13: Oda Y, Saito T, Tateishi N, Ohishi Y, Tamiya S, Yamamoto H, Yokoyama R, Uchiumi T, Iwamoto Y, Kuwano M, Tsuneyoshi M. Related Articles, Links
Abstract ATP-binding cassette superfamily transporter gene expression in human soft tissue sarcomas.
Int J Cancer. 2005 May 10;114(6):854-62.
PMID: 15609299 [PubMed - in process]
14: Zevallos-Giampietri EA, Yanes HH, Orrego Puelles J, Barrionuevo C. Related Articles, Links
Abstract Primary meningeal Epstein-Barr virus-related leiomyosarcoma in a man infected with human immunodeficiency virus: review of literature, emphasizing the differential diagnosis and pathogenesis.
Appl Immunohistochem Mol Morphol. 2004 Dec;12(4):387-91. Review.
PMID: 15536343 [PubMed - indexed for MEDLINE]
15: Bridge RS Jr, Bridge JA, Neff JR, Naumann S, Althof P, Bruch LA. Related Articles, Links
Abstract Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study.
J Clin Pathol. 2004 Nov;57(11):1172-8.
PMID: 15509679 [PubMed - indexed for MEDLINE]
16: Harms D. Related Articles, Links
Abstract [Soft tissue malignancies in childhood and adolescence. Pathology and clinical relevance based on data from the kiel pediatric tumor registry]
Handchir Mikrochir Plast Chir. 2004 Oct;36(5):268-74. German.
PMID: 15503256 [PubMed - indexed for MEDLINE]
17: Grogg KL, Macon WR, Kurtin PJ, Nascimento AG. Related Articles, Links
Abstract A survey of clusterin and fascin expression in sarcomas and spindle cell neoplasms: strong clusterin immunostaining is highly specific for follicular dendritic cell tumor.
Mod Pathol. 2005 Feb;18(2):260-6.
PMID: 15467709 [PubMed - in process]
18: Fetsch JF, Laskin WB, Michal M, Remotti F, Heffner D, Ellis G, Furlong M, Miettinen M. Related Articles, Links
Abstract Ectopic hamartomatous thymoma: a clinicopathologic and immunohistochemical analysis of 21 cases with data supporting reclassification as a branchial anlage mixed tumor.
Am J Surg Pathol. 2004 Oct;28(10):1360-70.
PMID: 15371953 [PubMed - indexed for MEDLINE]
19: Spencer L, Jukic D. Related Articles, Links
Abstract A 71-year-old man with spindle-cell neoplasm of unknown origin: a difficult-to-diagnose clear-cell sarcoma.
Dermatol Online J. 2004 Jul 15;10(1):8.
PMID: 15347490 [PubMed - in process]
20: van Dartel M, Hulsebos TJ. Related Articles, Links
Abstract Characterization of PMP22 expression in osteosarcoma.
Cancer Genet Cytogenet. 2004 Jul 15;152(2):113-8.
PMID: 15262428 [PubMed - indexed for MEDLINE]

SARCOMAs come from cells which normally make nerve, muscle, bone, cartilage or fibrous tissue (vs breast cancer which mostly comes from cells which normall form linings of ducts/glands). Their aggressiveness is usually proportional to the degree to which they lose their differentiation (high grade being very differentiated). Cells which are differentiated utilize their energy to make products and serve their function; undifferentiated cells stop serving their function and spend most of their energy reproducing.
I am sure the National Cancer Institute website has non-technical as well as technical information,

Good luck!

LANI