Janet
02-11-2004, 07:18 PM
Hello Angela.
This is the first time I've posted here. I usually post on the general b/c board as Elle......but my real name's Janet. (It's a boringly long story :))
I've been reading through the posts looking for help with my own situation and came across your post about sugar and cancer on page 2. Here are some links with lots of info and the answers to your question "why no sugar". I hope this helps.
One important fact that I don't think is covered in any of these links is the fact that insulin blocks the formation of a very important binding protein. I'll try to keep it simple. Your body produces a growth factor called IGF-1 (Insulin-Like Growth Factor). Most b/c cells have receptors for IGF and when IGF-1 is attached to these receptors it stimulates the cancer cells in exactly the same way as oestrogen does with ER+ cells.
One of the ways that Tamoxifen actually works is by lowering the levels of free circulating IGF-1. Although your body makes IGF-1, the liver (if memory serves me right) also produces a binding protein called IGFBP3. It's job is to bind with any free circulating IGF, rendering it harmless. If IGF isn't bound to this protein then it is free to dock on to any receptors on the cancer cells and tells them to grow. So this binding protein is very important if you have b/c.
When you eat sugar of any kind, insulin is produced as a direct result. Insulin stops the formation of the binding protein that you need to inactivate the IGF. So, the less sugar you eat, the less free circulating IGF you have.....in theory anyway :)
I hope that wasn't too confusing. I do have research to support this, so if you would like it let me know.
Here are the links I promised.
http://www.mercola.com/2000/oct/8/sugar_cancer.htm
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12208894&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9770725&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8375922&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9806115&dopt=Abstract
http://www.mercola.com/article/sugar/sugar_cancer.htm
http://www.mercola.com/article/Diet/sugar/dangers_of_sugar.htm
Hope this helps.
Love,
Janet
This is the first time I've posted here. I usually post on the general b/c board as Elle......but my real name's Janet. (It's a boringly long story :))
I've been reading through the posts looking for help with my own situation and came across your post about sugar and cancer on page 2. Here are some links with lots of info and the answers to your question "why no sugar". I hope this helps.
One important fact that I don't think is covered in any of these links is the fact that insulin blocks the formation of a very important binding protein. I'll try to keep it simple. Your body produces a growth factor called IGF-1 (Insulin-Like Growth Factor). Most b/c cells have receptors for IGF and when IGF-1 is attached to these receptors it stimulates the cancer cells in exactly the same way as oestrogen does with ER+ cells.
One of the ways that Tamoxifen actually works is by lowering the levels of free circulating IGF-1. Although your body makes IGF-1, the liver (if memory serves me right) also produces a binding protein called IGFBP3. It's job is to bind with any free circulating IGF, rendering it harmless. If IGF isn't bound to this protein then it is free to dock on to any receptors on the cancer cells and tells them to grow. So this binding protein is very important if you have b/c.
When you eat sugar of any kind, insulin is produced as a direct result. Insulin stops the formation of the binding protein that you need to inactivate the IGF. So, the less sugar you eat, the less free circulating IGF you have.....in theory anyway :)
I hope that wasn't too confusing. I do have research to support this, so if you would like it let me know.
Here are the links I promised.
http://www.mercola.com/2000/oct/8/sugar_cancer.htm
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12208894&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9770725&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8375922&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9806115&dopt=Abstract
http://www.mercola.com/article/sugar/sugar_cancer.htm
http://www.mercola.com/article/Diet/sugar/dangers_of_sugar.htm
Hope this helps.
Love,
Janet