Jeff...

[Rozebud]

I would. I'm her2+ and on herceptin and tamoxifen. Any studies saying they are contraindicated (or whatever the word is) would be greatly appreciated!

[jeff]

Hey Rozebud,

Here's a few good places to start. All suggest that her2 tumors might be tamoxifen resistant, BUT that that adding herceptin (or iressa) might be effective.

Jeff
http://jncicancerspectrum.oupjournals.org/cgi/content/full/jnci;96/12/895?view=full

http://jncicancerspectrum.oupjournals.org/cgi/content/abstract/jnci;96/12/926?view=abstract

http://jncicancerspectrum.oupjournals.org/cgi/content/full/jnci;96/12/891-b?view=full

[jeff]

And here's a really good review article by Allison Jones, of the UK, who also was kind enough to answer my email when I wrote him to ask some follow ups about this...

Best,
Jeff

http://annonc.oupjournals.org/cgi/content/full/14/12/1697