View Full Version : Breast Cancer Meeting Highlights
- Consistent High False Negative Rate of HER2 qRT-PCR of Oncotype DX® (0 replies)
- Changes in Gene Expression after One Dose of Trastuzumab (0 replies)
- Early decrease in CTC level = response to Tykerb & Capecetibine in Her2+ brain mets (0 replies)
- T-DM1 and Pertuzumab as New Tools for HER2 Specific Antibody-Therapy (0 replies)
- Adipose Tissue in Breast Cancer: an Active Participant in Breast Cancer Progression (0 replies)
- Zoledronic Acid Reverses the Epithelial-Mesenchymal Transition (0 replies)
- The Cytotoxicity of Select Neutrophils in Cancer Patients (0 replies)
- Adjuvant Therapy in Patients with a Borderline HER-2 Status (0 replies)
- Novel Approaches to Breast Cancer Management in Low-Income Countries (0 replies)
- SABCS 2011 - videos + (4 replies)
- SABC on Cure (1 replies)
- Nov. 17 CancerConnect - CIM - Ask the expert (0 replies)
- Upcoming conferences in Sweden (0 replies)
- 2011 ASCO Podcasts (0 replies)
- ASCO 2011 from CURExtra (0 replies)
- New Directions in the Treatment of Patients With HER2-positive Breast Cancer (3 replies)
- St. Gallen Endocrine classifications and recurrence (0 replies)
- Impact of a change of body mass index following adjuvant tx (0 replies)
- Long-term responders to trastuzumab (0 replies)
- Nine versus 52 weeks of adjuvant trastuzumab in early breast cancer (2 replies)
- Protection of adjuvant trastuzumab in sites of early relapses (0 replies)
- Good results for small tumors tx with Herceptin (0 replies)
- Oncotype returns high false negative of Her2 results (2 replies)
- ASCO 2011 abstracts available (1 replies)
- Effects of bc protection of pregnancy on Her2- vs Her2+ bc (6 replies)
- PTEN deletion: An underlying mechanism for PTEN loss in breast cancer (0 replies)
- Enhancement of trastuzumab selectivity via cyclic complex formation (0 replies)
- Lab Model of Lapatinib Resistance (0 replies)
- Serotonin signaling plays a role in regulation of autophagy in breast cancer cells (3 replies)
- In vitro cell and in vivo animal studies of the demethylating agent in treating HER2+ (0 replies)
- Overcoming trastuzumab resistance with the irreversible Pan-HER inhibitor neratinib (0 replies)
- Regulation of Her-2 in long-term letrozole resistant cells by HSP-90 (0 replies)
- Night work and breast cancer risk: CECILE study (0 replies)
- Sustained release curcumin microparticles show promise as chemopreventive against HER (0 replies)
- Curcumin suppresses the expression of HER-2 gene (0 replies)
- Amplification of tumor immunity with cryoablation (0 replies)
- HER2/neu positive receptor status is associated with a low DNA repair capacity in bc (0 replies)
- A difference of HER-2 amplification index between luminal B and HER2 enriched subgrou (0 replies)
- Epigenetic portraits of human breast cancers (0 replies)
- Effects of aerobic training to improve cardiovascular function after chemo (0 replies)
- Exposure to gefitinib during premalignant risk window/lifelong protection to MMTV mic (0 replies)
- Entosis: Adhesion, autophagy, and murder (0 replies)
- Autophagy and HER2 interaction in mammary tumorigenesis (0 replies)
- Heat shock protein vaccines for immunotherapy of Her-2/neu positive breast cancers (0 replies)
- Signaling networks potentially involved in breast cancer metastasis to the brain (0 replies)
- Short-term pregnancy levels of estradiol delays Her-2+ mammary tumor development (0 replies)
- Delphinidin dietary anthocyanidin modulates EGFR/HER-2 signaling pathway in bc cells (0 replies)
- Endoxifen exhibits anti-tumor activity in Her2+, tamox resistant tumors in lab (1 replies)
- Biomarkers of Response to Herceptin + Chemo (0 replies)
- Research on reversing Herceptin resistance (0 replies)
- Social isolation stress-induced obesity increases mammary cancer risk (0 replies)
- Combating trastuzumab resistance by targeting Src (0 replies)
- Metformin potentiates the efficacy of radiotherapy (0 replies)
- Targeting Her2 - Podcasts from SABCS (0 replies)
- 'Aging in the know' from Health In Aging (0 replies)
- c4yw (0 replies)
- Targeting Her2: Beyond Trastuzumab (2 replies)
- Phase I study of a Her2/Her3 heterodimer drug (0 replies)
- Phase II study of T-DM1 + PI3K Inhibitor (0 replies)
- Evidence for Treatment of Metastatic Breast Cancer beyond 2nd Line (0 replies)
- Phase II Multicenter Study of Docetaxel and Bevacizumab (Bev) +/- Trastuzumab for MBC (0 replies)
- Use of Selective COX-2 Inhibitors and Breast Cancer Recurrence (0 replies)
- Dual Estrogen Effects on Breast Cancer (0 replies)
- Oral Contraceptive Use and Overall Breast Disease Risk (0 replies)
- Insulin Resistance, Diabetes Mellitus and Breast Cancer and moderate exercise (0 replies)
- Relationship between Vitamin D Deficiency and Breast Cancer Histology (0 replies)
- Resolving the problem of intra tumoral Her2 heterogeneity (1 replies)
- Next-Generation Transcriptome Sequencing of the Normal Breast (0 replies)
- Could We Reduce the Number of Exams in the Follow-Up of Breast Cancer Survivors (0 replies)
- Seroma Formation Is Associated with Lymphedema-Related Symptoms (0 replies)
- Impact of Adjuvant Trastuzumab on Local Regional Recurrence (0 replies)
- Patterns of Relapse According to Subtypes in LNN BC (0 replies)
- Symptom Burden of patients receiving chemo + Herceptin improves when chemo stops (0 replies)
- Concurrent vs. Sequential Administration of Adjuvant Trastuzumab (0 replies)
- Investigating Early Features of Aromatase Inhibitor-Induced Arthralgia (0 replies)
- Cognitive Effects of Endocrine Therapy in Patients with Breast Cancer (7 replies)
- ER Positive Screen Detected Breast Cancers Do Not Require Chemotherapy (0 replies)
- Evaluating the Efficacy of chemo in postmeno ER+ pts (1 replies)
- BreastCancerTrials.org: Nationwide Clinical Trial Matching Service (0 replies)
- Truncated ERBB2 Receptors: Diagnostic and Therapeutic Targets (0 replies)
- Increase of Coronary Artery Stenosis after Radiation for Breast Cancer (0 replies)
- HERA subset analysis: effect of age on Her2+ outcomes (0 replies)
- Correlation of Oncotype Dx Recurrence Score and Luminal Subtypes of Breast Cancer (0 replies)
- False Positive HER-2 Testing by Fluorescence In Situ Hybridization (0 replies)
- Fat cells regulate bc functions differently in lean and obese women (0 replies)
- Study: Higher BMI predicts poor neoadj response among Her2+ (0 replies)
- Plasticity of the ER and HER2 Signaling Networks (0 replies)
- Heat Shock Protein 90 Inhibitors: New Targeted Therapy To Overcome AI Resistance (0 replies)
- Lapatinib Resistance Confers Cross-Resistance to Microtubule Inhibitors (1 replies)
- Hormone-Receptor Expression and Activity of Trastuzumab-Based Therapy (0 replies)
- BMI related to effectiveness of extended AI therapy (0 replies)
- Weight loss in high risk postmeno women alters serum biomarkers assc w/bc (0 replies)
- Competing Causes of Mortality vs. Breast Cancer Mortality (0 replies)
- Sentinel Node Trial: outcomes for micro and macro node mets (0 replies)
- Drug Development – Targeting HER2 beyond Trastuzumab (0 replies)
- Tumor Remissions under Trastuzumab Therapy (0 replies)
- Can Resistance to Trastuzumab Be Reversed by Endocrine Therapy? (1 replies)
- In the Lab: Development of a Her2 targeted anthracycline (1 replies)
- Responses to Subsequent Anti-HER2 Therapy after Treatment with T-DM1 (0 replies)
- Efficacy and Safety of Neratinib (HKI-272) in Combination with Paclitaxel (1 replies)
- Study of the best sequence for administration of Tykerb and AI's (0 replies)
- Increased Rate of HER2-Positive Breast Cancers among Women w/Germline TP53 Mutations (2 replies)
- LACE Study: Vitamin use and bc outcomes (0 replies)
- Aspirin Use and the Risk of Breast Cancer (0 replies)
- Early Detection of Recurrent Breast Cancer Using Metabolite Profiling (0 replies)
- Consistent Prognostic Impact of HER2 Status Over Time (0 replies)
- PR- bc patients have poorer outcomes when tx with SERMs (0 replies)
- Androgen Receptor Expression in BC related to outcomes (0 replies)
- Influence of Body Mass Index on Presence of Disseminated Tumor Cells (0 replies)
- Using Serum Her2 levels to monitor response to neoadj chemo (1 replies)
- In Lab: Curcumin active against Her2 and may overcome Herceptin Resistance (1 replies)
- Phase II Trial Administering a HER2/neu-Derived Peptide vaccine w/Herceptin (0 replies)
- Metronomic Chemotherapy Inhibits Tumor Growth and Metastases Development in mice (1 replies)
- Factors Associated with Job Resumption after Primary Breast Cancer Treatment (0 replies)
- How Common Is Sexual Dysfunction among Women with Early Stage Breast Cancer? (0 replies)
- Circadian Clock Genes predict neoadj chemo response (0 replies)
- Anti-Herceptin antibodies associated with longer PFS in Herceptin tx pts (0 replies)
- Study sugguests ER+ P13K activated tumors have strong Herceptin response (0 replies)
- Ki67 Discriminates Luminal A & B BC better than Her2 status (0 replies)
- Her2+ BC account for large portion of Mammographic Failure to detect (0 replies)
- Discordant Pet scans (ER & Gloucose) predicts ER insensitivity in Her2+ Stage IV pts (1 replies)
- Tykerb + Fulvestrant not useful in Her2+ ER+ metastatic pts. tx w/AI (0 replies)
- Lab Findings: Tykerb + Insulin/Insulin-like growth factor receptor for ER resistance (0 replies)
- Lab Findings: T-DM1 + PK13 inhibitor shows promise for Her2+ bc (0 replies)
- Discordance in Hormone Receptor and HER2 Status in BC during Tumor Progression (0 replies)
- Herceptin + Pertuzumab active in Her2+ bc w/o chemo - NeoSphere study (0 replies)
- Online Conference San Antonio Breast Cancer Symposium (0 replies)
- Her2+ Correlates to Coexisting Invasion in DCIS (0 replies)
- Multi-Modality tx improves brain met survival (0 replies)
- Brain Met outcomes for Her2+ patients enrolled in LEAP (0 replies)
- Her2+ patients Retain an Immunological Proficiency Compromised in Her2- cases (0 replies)
- TN and Her2 bc more chemo sensitive but have higher rate of brain mets (0 replies)
- Phase II trial of 4 drug combination for early Her2+ bc (0 replies)
- Neoadjuvant trial of Concurrent Trastuzumab and Paclitaxel without Anthracycline (0 replies)
- Response to neoadjuvant chemo + Herceptin predicts survival (0 replies)
- No anti-tumor effects seen in adding Zolendraic acid to chemo (1 replies)
- Retesting Her2 status in metastatic patients cost effective and relevant (0 replies)
- Short-term exposure to pregnancy level ER delays Her2+ tumor development (0 replies)
- Short-term exposure to pregnancy ER levels alters bc pathway development (0 replies)
- Safety of High Dose Vitamin D in pre-meno women (0 replies)
- Chinese Herb Fructus Cornii prevents ER+ BC in the lab (0 replies)
- Protective Effect of Dietary Intervention limited to high baseline Testosterone (0 replies)
- Omega-3 Fatty Acids for Chemoprevention (0 replies)
- Tamoxifen, Flaxseed and Tumor Growth (4 replies)
- Molecular Biomarkers for Resistance to Trastuzumab (0 replies)
- BC Stem Cells survive Herceptin by downregulation of Her2 (0 replies)
- Toxicity of Adjuvant Endocrine Therapy in Postmenopausal Breast Cancer Patients (0 replies)
- High baseline inflammatory signature results in lower response to AI's (0 replies)
- Impact of BMI on endocrine tx in postmeno HR+ BC (0 replies)
- Obesity at Dx associated with worse outcomes in HR+ BC (0 replies)
- CYP2D6 metabolism unrelated to Tamoxifen benefit (0 replies)
- FIRST study: Arimdex vs. Fulvestrant for Advanced BC (0 replies)
- Colon cancer risk (2 replies)
- The role of autophagy inhibition as a neoadjuvant therapy for DCIS (0 replies)
- Adjuvant trastuzumab therapy in tumors smaller than 1 cm (0 replies)
- Is it safe to use transtuzumab for the treatment of breast cancer during pregnancy? (0 replies)
- The prognostic and predictive impact of BMI on clinical outcome of HER2-positive bc (5 replies)
- Evaluation of trastuzumab without chemotherapy as a postoperative adjuvant therapy (0 replies)
- A phase I study to assess the safety, tolerability, and PK of ARRY-380, an oral HER2 (0 replies)
- Estrogen receptor positivity in normal breast epithelium from women with breast cance (0 replies)
- Subcutaneous testosterone-anastrozole implant therapy in breast cancer survivors (1 replies)
- Correlation between diabetes and ER/HER2 status in African Americans (0 replies)
- Survival after supraclavicular recurrence of breast cancer (0 replies)
- Can whole-brain irradiation (WBRT) be replaced by radiosurgery? (0 replies)
- Breast cancer at the extremes of age: Predicting recurrence and mortality (0 replies)
- Long-term outcome of node-negative early breast cancer patients (0 replies)
- Molecular predictive factors of response to taxanes (T) and anthracyclines (A) in bc (0 replies)
- Is microcalcification on mammography relrelated to bone metastasis & bad prognosis? (0 replies)
- In situ carcinoma (ISC) accompanying small (≤ 1 cm) invasive breast carcinoma (IBC) (0 replies)
- Genomic profile of screen- and symptom-detected breast cancers and association w/ DFS (0 replies)
- Association of phosphorylated-HER2 with relapse in patients (0 replies)
- Is age an independent predictor of survival and time to recurrence in breast cancer? (0 replies)
- A couple ASCO 2010 related links (3 replies)
- Method of detection of DCIS to predict HER2 overexpression (0 replies)
- Impact of BMI on clinical outcome of HER2-positive breast cancer (0 replies)
- Circulating tumor cells (CTCs) and association with survival in molecular subtypes (1 replies)
- Survival benefit of neck dissection for patients w/bc w/supraclavicurlar LN mets (2 replies)
- Safety and efficacy of low-dose metronomic chemotherapy with capecitabine (1 replies)
- Early detection of recurrent breast cancer using metabolite profiling (0 replies)
- Biomarker changes associated with the development of resistance to AIs (0 replies)
- Discordance in hormone receptor status in breast cancer during tumor progression (0 replies)
- Should liver metastases of breast cancer be biopsied to improve treatment choice? (0 replies)
- False-negative HER2 tests with appropriate positive controls (0 replies)
- Tykerb treatment for DCIS - study (0 replies)
- HER2+ gene expression signature specific for trastuzumab resistance and poor prognosi (0 replies)
- Good news for triple positive (ER+/PR+/Her2+) bc (1 replies)
- Cause-specific and all-cause mortality of HER2-positive, node-negative, T1a & T1b bc (0 replies)
- For T1a,b,N0M0 Her2+ patients not treated with chemo or Herceptin, age at dx importan (0 replies)
- Association of gene copy number alterations with prognostic subtypes (0 replies)
- Gene signature of metformin actions on primary breast cancer (0 replies)
- Dose-dependent interaction between tamoxifen and antidepressants on patient complianc (0 replies)
- Beta-blockers and ACE inhibitors in the prevention of trastuzumab-related cardiotoxic (0 replies)
- CK-19 mRNA-positive CTCs and Herceptin treatment (0 replies)
- Ovarian suppression + endocrine therapy + zoledronic acid in premeno bc patients (0 replies)
- ASCO: Leptin & High BMI May Reduce Her2+ Survival (2 replies)
- What ASCO Can Tell You About Biotechs (0 replies)
- Statistics from Peru for DFS and OS in Her2+ & ER+/- BC (6 replies)
- Correlation of molecular and clinically distinct phenotypes in HER2+ ER+ BC (0 replies)
- Impact of body mass index (BMI) on endocrine therapy in premenopausal breast cancer (0 replies)
- Treatment by subtype: a neoadjuvant study (0 replies)
- June 2010: Updates from the 2010 ASCO Annual Meeting (0 replies)
- 2010 ASCO Abstracts (0 replies)
- Breast carcinoma DNA methylation profiles associated w/tumor size, alcohol & folate (1 replies)
- Plasma coenzyme Q10 levels and postmenopausal breast cancer risk (0 replies)
- Molecular markers for breast carcinogenesis models induced by environment & ER (0 replies)
- Potential of PET imaging to predict the response to anti-HER2 therapy in breast cance (0 replies)
- Cyclin E amplification, a novel mechanism of resistance to trastuzumab in HER2+ bc (0 replies)
- Temporal changes of gene expression in bc cells during adaptation to ER deprivation (0 replies)
- FOXO1A is a target for HER2 overexpressing breast tumors (0 replies)
- Metformin enhances tumor regression and reduces tumor burden in mice (0 replies)
- Mammotrophic hormone score and risk of postmenopausal breast cancer (0 replies)
- Urine biomarkers outperform serum biomarkers in the diagnosis of various human cancer (0 replies)
- Autophagy inhibition in endocrine resistant human breast cancer cell lines (0 replies)
- Gene expression profiling of hormone-regulating pathways (0 replies)
- Salivary biomarkers for breast cancer detection (0 replies)
- Circadian disruption and breast carcinogenesis (0 replies)
- Gene expression profiling in circulating cells (CTCs) a tool for early mets detection (0 replies)
- Aromatase expression promotes breast cancer tumorigenesis and bone metastasis (0 replies)
- Newly designed nanobioconjugate for tx of Her2+ bc (1 replies)
- M1 is a candidate proteasome activator drug in breast cancer that down-regulates Her2 (0 replies)
- Proteomics-based characterization of pathways involved in tamoxifen resistance (0 replies)
- Paradoxical actions of a c-Src inhibitor on long-term ER deprived cells (1 replies)
- Expression patterns of the ERBB2 gene and associations with breast risk and survival (0 replies)
- Alternate mechanisms of PI3K pathway activation among subtypes of DCIS (0 replies)
- Copy number variation in low- and high-grade breast tumors (0 replies)
- 14-3-3zeta cooperates with ErbB2 in DCIS to invasive bc progression (0 replies)
- Activation of mTOR in obesity persists after weight loss (0 replies)
- High expression of CXCL13 was associated with lower risk for relapse in Her2+ BC (0 replies)
- Curcumin analogues are cytotoxic towards ER- BC lines (1 replies)
- Obese mice that lose weight retain higher bc risk via mTOR pathway (0 replies)
- Hypoxia regulates the breast cancer stem/progenitor cell population (0 replies)
- Building an accelerated path to tailored adjuvant cancer therapy (0 replies)
- Molecular basis of correlation between HER2+ and sensitivity to anthracyclines (0 replies)
- Heat shock protein 90 inhibitors: New mode of therapy to overcome AI resistance (0 replies)
- MiR-21 upregulation in breast cancer cells leads to PTEN loss and Herceptin resistanc (0 replies)
- Deletion of cyclooxygenase-2 in mouse mammary epithelial cells delays bc onset (0 replies)
- Intermittent treatment of ER+ BC with exemestane: Translational research (0 replies)
- Body fat %, inflammation, and bc survival (0 replies)
- gene expression profiles reveals subtype-specific drug sensitivities among bc lines (0 replies)
- Diabetes pharmacotherapy: A potential modifier of breast cancer prognosis? (0 replies)
- Cyclin D1 regulaties progesterone receptor expression (0 replies)
- Leptin-induced breast cancer cell migration requires upregulation of survivin (0 replies)
- The topography of estrogen receptor expression in the human breast (0 replies)
- Breast cancer stem cells play a role in trastuzumab resistance in mouse models (0 replies)
- Chloroquine + Her2 inhibitors = growth inhibition (0 replies)
- HER2 expression occurs early in breast cancer dissemination (0 replies)
- ASCO (Dec. 2009) Reports (0 replies)
- Video and audio from SABC 2009 (and more) (2 replies)
- Fatty Acid Synthase (FASN) as a Therapeutic Target for Breast Cancer Metastasis (0 replies)
- Outcomes of Stereotactic Radiosurgery in Her2+ brain mets (0 replies)
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