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Diet and Nutrition By popular demand our nutritional message board. This board will be monitored by a Registered RD who is certified in oncology by the American Dietetic Association

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Old 04-02-2012, 08:08 AM   #1
Hopeful
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From 60 Minutes: Is Sugar Toxic?

http://www.cbsnews.com/8301-18560_16...in;cbsCarousel

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Old 04-02-2012, 08:58 AM   #2
1rarebird
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Re: From 60 Minutes: Is Sugar Toxic?

Dr. Cantley's explanation that sugar causing spikes in insulin that can stimulate cancer cells that have insulin receptors (1/3 of breast cancer cells were mentioned as being this way), seems to support the idea that Metformin (the diabetes medication) should be helpful to many breast cancer patients since Metformin has been shown to reduce insulin spikes when reacting to the ingestion of sugar and other carbohydrates. Well, at least this is the way I am reading this news---bird
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Old 04-03-2012, 09:41 AM   #3
TanyaRD
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Re: From 60 Minutes: Is Sugar Toxic?

I think you are right about the Metformin and I know of at least one person on the listserv who has started Metformin. When I saw the headline for this article I didn't expect much valuable content (more media hype) however, I have to admit it is very thought provoking. I will be interest to read the cardiac study referenced in the article. As an RD I frequently counsel patients to limit sugars for high triglyceride levels but noting that sugars may also increase LDL levels is very interesting. Toxic is a strong word but as I thought about that I realized I have come to classify saturated fat and trans fats as such. I just read another article in Nutrition Action entitiled "Sugar Belly" (rather than beer belly) which discussed the theory that fructose intake (mostly from added sugars-not fruit) increases abdominal, visceral fat thus increasing cardiac risk, cancer risk, etc. Intuitively, we know we shouldn't eat so much sugar. None would be quite a challenge. Significantly limiting intake is no doubt of benefit.

Thanks for sharing this article.
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Old 04-03-2012, 09:53 AM   #4
Mtngrl
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Re: From 60 Minutes: Is Sugar Toxic?

I didn't know that some tumors have insulin receptors. Yikes.
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4/19/11 Diagnosed invasive ductal carcinoma; 2.3 cm tumor, 1 axillary lymph node
HER-2+++, weakly ER+ (10%)
4/29/11 CT scan shows suspicious lesions on liver and lungs
5/17/11 liver biopsy
5/24/11 liver met confirmed--
Stage IV at diagnosis
5/27/11 Begin weekly Taxol & Herceptin for 3 months (standard of care at the time of my DX)
7/18/11 Switch to weekly Abraxane & Herceptin due to Taxol allergy
8/29/11 CT scan shows no new lesions & old lesions shrinking
9/27/11 Finish Abraxane. Herceptin every 3 weeks. Begin taking Arimidex
10/17/11--Brain MRI--No Brain mets
12/5/11 PET scan--Almost NED
5/15/12 PET scan shows progression-breast/chest (mediastinal lymph nodes)/spine (one vertebra)
5/22/12 Stopped taking Arimidex; stay on Herceptin
6/5/12 CT scan
shows everything stable
6/11/12 Started Tykerb and Herceptin on clinical trial (w/no chemo)
8/1/12 CT scan--stable.
9/24/12 CT scan--No new mets. Everything stable.
11/19/12-Stable CT scan
12/13/12 CT Scan--NED

3/11/13 CT Scan--two small new possible mets and odd looking area in left lung getting larger.
4/2/13--Biopsy of suspicious area in lower left lung. Mets to lung confirmed (but it says cancer cells are "scant").
4/30/13 Began Kadcyla/TDM-1
8/16/13 PET scan "mixed," with some areas of increased uptake, but also some definite improvement, so I'll stay on TDM-1/Kadcyla.
11/11/13 Finally got hormone receptor results from lung biopsy of 4/2/13. My cancer is no longer ER positive.
11/13/13 PET scan mixed results again. We're calling it "stable." Problems breathing on exertion.
2/18/14 PET scan shows a new lesion and newly active lymph node in lung, other progression. Bye bye TDM-1.
2/28/14 Begin Herceptin/Perjeta every 3 weeks.
6/8/14 PET "mixed," with no new lesions, and everything but lower lungs improving. My breathing is better, though.
8/18/14 PET "mixed" again. Upper lungs & one spine met stable, lower lungs less FDG avidity, original tumor more avid, one lymph node in mediastinum is more avid.
9/1/14 Begin taking Xeloda one week on, one week off. Will stay on Herceptin and Perjeta every three weeks.
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Old 08-09-2012, 02:36 AM   #5
R.B.
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Re: From 60 Minutes: Is Sugar Toxic?

A recent news item which has a section discussing glucose insulin and sugar

http://www.cbsnews.com/video/watch/?id=7403942n
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