Wonderful Abstract - nice to see it in print!

[Donna]

Wow - did you see this! The last line is the best:



: Curr Oncol Rep. 2007 Jan;9(1):9-16.<SCRIPT language=JavaScript1.2><!--var PopUpMenu2_LocalConfig_jsmenu3Config = [ ["ShowCloseIcon","yes"], ["Help","window.open('/entrez/query/static/popup.html','Links_Help','resizable=no,scrollbars= yes,toolbar=no,location=no,directories=no,status=n o,menubar=no,copyhistory=no,alwaysRaised=no,depend =no,width=400,height=500');"], ["TitleText"," Links "]]var jsmenu3Config = [ ["UseLocalConfig","jsmenu3Config","",""]]//--></SCRIPT><SCRIPT language=JavaScript1.2><!--var Menu17164042 = [ ["UseLocalConfig","jsmenu3Config","",""], ["Books","window.top.location='http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=pubmed_AbstractPlus&cmd=Retrieve& db=pubmed&list_uids=17164042&dopt=Books'","",""]]//--></SCRIPT> Links

<DD class=abstract id=abstract17164042>The Use of HER2 Modulation in the Adjuvant Setting.

• Johnson PH,
• Esteva FJ.

and Molecular & Cellular Oncology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1354, Houston, TX 77230-1439, USA. festeva@mdanderson.org.

Amplification of the her-2/neu gene is associated with poor prognosis in patients with early-stage and metastatic breast cancer. Trastuzumab is a humanized monoclonal antibody directed against the HER2 protein, which is overexpressed in approximately 25% of patients with primary invasive breast cancer. Randomized phase III clinical trials showed that administration of trastuzumab in combination with chemotherapy or following chemotherapy significantly improves disease-free and overall survival rates in patients with early-stage HER2-positive breast cancer. The integration of trastuzumab in the adjuvant setting is changing the natural history of HER2-driven breast cancer from one of the worst subtypes to one that is highly curable with available therapy.

PMID: 17164042 [PubMed - in process]

</DD>

[tricia keegan]

Donna thanks for posting this,just what I needed.
Good news for a change!
Tricia

[Karen W]

Just wanted to bump this post to the top.

Thanks for the wonderful information, Donna.

Karen

[Carolyns]

Hi Donna,

Great, thanks for posting. I copied and pasted to the Young Survival Coalition website and referenced this site and your posting. I hope you don't mind.

Here is the link:
http://www.youngsurvival.org/young-women-and-bc/bbs/

[Mary Anne in TX]

I just love good (GREAT) news!

Thanks, Donna, for taking time to post this!

[suzan w]

thank you, Donna..."highly curable" music to our ears!

[Chelee]

Donna, I started to read your post and the MINUTE I saw the words "The last line is the best", you had me! I JUMPED right now to read that last line...I just couldn't wait after you said that. lol

That is so NICE to see in print. I did go back and read the rest of it in case you wondered. haha Thanks so MUCH for posting that. As someone else said, music to my ears!

Chelee