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Old 12-11-2019, 12:37 PM   #2
donocco
Senior Member
 
Join Date: Oct 2013
Posts: 474
Re: SABCS: Tucatinib 'game changing' vs HER2+ MBC, especially w brain mets

Lani

This is good news. Tucatinib is the drug that went by the experimental name of ONT-380 or something like that, correct. If it is it has good central nervous system penetration and the diarrhea is less than Tykerb because Tucatinib only acts on Her-2 not on Her-1. It seems to be a definite advance.
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