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01-20-2007, 09:21 AM
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#21
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Senior Member
Join Date: Jul 2006
Location: Shingle Springs, CA - near Sacramento
Posts: 295
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Dose Dense
Good Morning All,
I did dose dense AC and T.
Donna
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01-20-2007, 09:50 AM
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#22
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Member
Join Date: Dec 2006
Location: Millstadt, IL
Posts: 19
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4 DD A/C followed by 12 weekly Taxol with Herceptin
__________________
Linda2
DX 6/2005
Stage IIA, Grade I
ER/PR +, HER2 +++
Lumpectomy on Left breast 7/2005
No lymph nodes involved
4 cycles of A/C
12 weekly doses Taxol and Herceptin
33 Rads
Herceptin for one year ended 12/2006
Femara for 5 years
NED as of now
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01-20-2007, 09:56 AM
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#23
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Senior Member
Join Date: Nov 2006
Location: The Hudson Valley, New York
Posts: 124
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Sue is currently going through AC dense dose, every 2 weeks, 4 cycles. Taxol and herceptin are coming every week for 12 weeks, then herceptin for perhaps a year.
__________________
---Kevin and Sue---
Dx'd 10/06 IDC grade III/III
Er- pr- HER2 3+
MRM right breast 12/5/06
nodes negative
same day reconstruction started
(implants)
Stage II (2.2 cm tumor)
fairly extensive DCIS
Ct and Bone scans clean
Port placement 12/26/06
AC (4 cycles DD)to begin 1/2/07
Taxol/Taxotere (4 cycles DD)
Herceptin for one year
"There is no distinction between the one who gives, the one who receives, and the gift itself."- Hahn
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01-20-2007, 10:48 AM
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#24
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Senior Member
Join Date: Oct 2005
Location: Saratoga Springs New York
Posts: 136
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I had taxotere, carboplatin, herceptin every 3 weeks for six cycles. I have been on herceptin every 3 weeks since. (2 1/2 years). Sally
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01-20-2007, 11:08 AM
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#25
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Senior Member
Join Date: Sep 2005
Location: Lumberton, Mississippi
Posts: 118
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Had CAF every 3 weeks for 6 treatments.
Linda
__________________
Diagnosed 12/23/04
Biopsy 12/28/04
Lumpectomy 1/04/05
IDC, ER-PR-, HER2Neu+++
7mm tumor, Stage 1, Grade 3
6 CAF's
38 Rads
Finished 10/05
"Worry looks around. Sorry looks back. Faith looks up."
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01-20-2007, 02:11 PM
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#26
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Senior Member
Join Date: Aug 2006
Location: Franklin, MA
Posts: 131
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I had Taxol every 3 weeks to start (for 11 cycles). Had Herceptin every 3 weeks as well. Now I'm on Navelbine 3 weeks on/1 week off (while continuing the Herceptin every 3 weeks).
__________________
Diagnosed 10-03-2005 (34 wks pregnant, 38 yrs old)
Lumpectomy Nov-2005. 10/18 Lymph Nodes impacted
Mets to liver, spine & femurs (thus being stage IV right from the get-go)
ER-, PR-, HER2+
Taxol/Herceptin/Zometa started Dec-2005. 11 cycles of Taxol.
Sept-2006: PET/CT scan of mets to liver, spine and femurs - Stable. Activity in R breast & mediastinum (not seen in prior scans).
Navelbine (3 wks on/1 wk off) as of Oct--2006 & continued Herceptin (every 3 wks) & Zometa (every 6 wks)
Jan-2007: PET/CT Scan - Stable. Continued Nav. through March-2007, then Herc./Zom. only after that.
June-2007: PET/CT Scan - activity in mediastinum. Back on Navelbine as of July-2007.
Scanned Quarterly since Oct-2007 - a few small scares, but otherwise stable due to continuing weekly Navelbine, Herceptin and Quarterly Zometa.
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01-20-2007, 02:26 PM
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#27
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Senior Member
Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
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I had TCH and still don't understand why I was never even given the option of dose dense AC....or even REGULAR AC? O'well...
Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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01-21-2007, 05:32 PM
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#28
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Senior Member
Join Date: Dec 2006
Location: WHITESTOWN IN
Posts: 148
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I'm having DD AC every 2 wks x4 then Taxol every 2 wks x4. When I start the Taxol I start Herceptin every week for the 8wks of Taxol and then can switch to every 3wks.
__________________
DX IDC AT 42 12/7/06
2.2CM STAGE I GRADE 2
NODE NEG
PARTIAL 12/18/06
HER2+ /ER+(75%) PR+(5%)
4 DD AC CHEMO STARTING 1/10/07
4 DD Taxol Starting 3/5/07
1year weekly Herceptin starting 3/5/07
finished 2/18/08
changed to every 3 weeks 4/23/07
completed 33 radiation treatments 7/6/07
TAH and BSO 9/24/07
start Femarra 10/8/07
Started Neritinib trial 12/14/09
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01-21-2007, 06:45 PM
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#29
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Senior Member
Join Date: Sep 2005
Location: Los Angeles
Posts: 430
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Hi Rhonda,
4 ac every 3 weeks.
4 taxol with herceptin every three weeks
herceptin every three weeks for 48 weeks
XO
MCS ( maria)
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01-21-2007, 06:55 PM
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#30
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Senior Member
Join Date: Jul 2006
Location: ontario, canada
Posts: 48
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Hi Rhonda,
Starting last March, I had AC chemo every three weeks, although my 3rd and 4th sessions were deferred by one week due to low white counts. Taxol was also every three weeks, with no delays. I am now on Herceptin every three weeks for a year and Tamoxifen daily. My onc didn't even suggest DD therapy, I don't know why. Maybe it just isn't standard treatment here in Canada, as much as it is in the U.S.
__________________
Karen
"The Good Lord gave us mountains, so we could learn how to climb!"
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01-21-2007, 08:36 PM
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#31
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Senior Member
Join Date: Sep 2005
Location: Mountains of Virginia
Posts: 2,267
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I had 4 DD A/C every two weeks then 10 Taxol/Herceptin weekly. Continued Herceptin weekly until after rads. Then switched to herceptin every three weeks (completed 18 mos) and added Arimidex. Zometa added in Dec 06 for osteopenia.
________
Vaporizer Volcano
Last edited by sassy; 08-22-2011 at 09:01 AM..
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01-22-2007, 05:52 AM
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#32
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Senior Member
Join Date: Sep 2005
Location: Philadelphia
Posts: 301
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Rhonda-
I had CET (cytoxan/epirubicin/taxotere) every 3 weeks for 4 cycles, then lump/SNB, and then 2 more cycles of it...
Regards,
__________________
Shell
init diag 3/17/03-stage IIIC
ER-/PR-/HER2+++
CET x4 neo-adjuvant
lump & SNB 8/03
CET x2
radiation and herceptin/navelbine 11-03-1/04
1st reoccur to lymph nodes 8/04
complete axillary dissection 12/04
herceptin/taxotere til progression (lungs) 3/05
xeloda w/out lapatinib trial 6/05
lapatinib/tykerb added 4/06
ended trial 8/06 due to progression
doxil / avastin 11/06-12/06 - wasn't working
navelbine/herceptin/avastin 12/06/3/07 - progression
gemzar/carboplatin/tykerb 4/07
mri shows extensive mets to bone in pelvic area 6/07
switched to abraxane (3 on/1 off) + tykerb 6/07
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01-22-2007, 07:39 AM
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#33
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Senior Member
Join Date: Dec 2005
Location: Michigan
Posts: 230
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I had Dose dense AC then Taxol
__________________
Mary
Diagnosed 11/04 @39yrs. young
Stage IIB
2.5 cm, ER/PR- Her+++, grade 3
Partial Mast., 1/3 pos. node
1/05 full node dissection
4 A/C 4 Taxol DD, Herceptin 1 yr.
30X rads.
BRCA Negative
NED
Hope is the thing with feathers
That perches in the soul,
And sings the tune without the words,
And never stops at all -Emily Dickinson
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01-22-2007, 11:18 AM
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#34
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Senior Member
Join Date: Jan 2006
Location: ALEXANDRIA, VA
Posts: 40
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Hi Rhonda,
My regiment has been as follows: 11/04 - 2/05 Taxol, carboplatin & hercp
every 3 weeks .... 3/05 - 5/05 hercp only every 3 weeks .... 6/05 - 12/05
hercp & navelbiene every other week ..... 12/05 - 9/06 hecp & navelbiene
every 3 weeks .... 9/06 to present day hercp only every 3 weeks .....
Take care & God Bless,
Debbie
__________________
dx stage 4 ... 11/04
3.2 cm mass breast & liver mets..
her2 +++ ; er- ; pr -;
11/04 treated with hercp, taxol & carboplatin - every 3 wks
3/05 ned - stopped chemo; hercp only
5/05 reoccurence left breast
6/05 added navelbiene w/ hercp every other wk
7/05 mascetomy
12/05 ned ; same regiment- every 3 wks
3/06 & 7/06 ned
9/06 stopped navelbiene.. hercp only.. every 3 wks;
10/06 pet scan shows positive lymph node in pec
12/06 PET no change;
4/07 scan showed 4 abnormal nodes in right pec area ... these have increased in activity since last scan... will start back on weekly navelbeine & hercp
7/07 PET done ..this time it showed new nodules in both right & left lung area as well as increased activity in pec area..
8/07 started Taxol & Carboplatin with Hercp every 3 wks
10/07 PET done ...Great Report ... NED ....
11/07 continue with Hercp every 3 wks & do Taxol & Carboplatin every 6 wks
4/09 still on same regiment; 1 positive node in left lung and right pec area
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01-22-2007, 02:54 PM
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#35
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Senior Member
Join Date: May 2006
Posts: 144
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I had DD AC, now finishing up a year of weekly Herceptin.
- Anna
__________________
- Anna
Stage I - DX 9/2005 ER/PR-, HER2+, grade 3, DCIS, IDC multi-focal (1.05cm)
DD 4 A/C finished Jan 31, 2006
Herceptin weekly finished Jan 31, 2007
recurrence to chest wall on last month of Herceptin
Stage 3B - 3/15/07 - 2 carcinomas in dermal lymphatic
Rads finished 6/5/07
12x TH finished 9/10/07
12/07 - Clear scan!
3/08 - 4 month Melatonin trial
1/09 - osteoperosis - start Alendronate
2/09 - 4-month Simivastin trial
3/13 - take drug holiday after 5 years of Alendronate
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01-22-2007, 04:23 PM
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#36
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Senior Member
Join Date: Aug 2006
Location: PA
Posts: 188
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I had DD A/C.
__________________
Susan V - Pittsburgh PA
DX Age 37 on August 3, 2006
Stage 1 Grade 3
ER/PR + (Highly Positive)
Her 2 +++
1.3 & 1.2 tumors right breast
node negative
lumpectomy 8-15-06
A/C Began 9-5-06 Finished A/C 11/6/06
Port Placement 9-15-06
Negative Test for BRAC1 & BRAC2 10-25-06
Began Tamoxofin November 21, 2006
First Herceptin November 27, 2006 Continues every 3 Weeks
First Radiation Treatment December 11, 2006
35 Rads Completed
Final Herceptin Treatment November 12, 2007
Port Removal November 19, 2007
Living Life to the Fullest !!
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01-22-2007, 04:26 PM
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#37
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Senior Member
Join Date: Jul 2006
Location: Southern California
Posts: 30
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Taxotere/Carboplatin/Herceptin - 3 weeks...dose dense not an option
__________________
Stage IIb, dx 12-26-05, age 37
Lumpectomy 1-4-06, 1.1 cm idc
3/19 pos. nodes (sentinel node was neg.)
ER +, PR +, Her2 +
TCH, radiation, Lupron/Aromasin
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01-23-2007, 12:52 PM
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#38
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Senior Member
Join Date: Dec 2006
Posts: 136
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I did A/C every three weeks starting in January of 06. I then did Taxol every week for 12 weeks. I continue with Herceptin weekly; I have had 40 of those with 12 to go!
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01-23-2007, 02:58 PM
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#39
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Senior Member
Join Date: May 2006
Location: California
Posts: 668
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Herceptin weekly
Hi Sherry: I do herceptin every three weeks, the onc said that it does not matter the frequency, but the dosage does. I see some women on this site that do Herceptin weekly. Have you asked your doctor why weekly as opossed to every three weeks. Also what's the dosage for you/ Is it based on your weight? Thank you.
__________________
1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.
2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.
2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
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01-23-2007, 03:15 PM
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#40
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Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
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Had both
My first treatment was DD, weekly Adriamycin for 12 weeks. (Believe me - I never thought THAT would end!)
Followed by 4 Taxotere 3 weeks apart.
When treated for mets, it was weekly for 7 months until I reached what looked like (and was) NED.
Then went on the 3 week dose of Herceptin.
Are you compiling a chart, Rhonda??
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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