Optimum Treatment After Resection of Brain Met

[Freakzilla]

Hi Everyone,

As some of you know my Girlfriend had a solitary 4cm brain met removed via crainiotomy nearly 4 weeks ago. The tumour was completely removed. Body scans as of 6 weeks ago was completely clear.

As we understood it, the onc was then going to ask for a SRS boost to the area, and then maybe WBRT. Upon seeing the Onc last week this has now changed. They now recommend just WBRT. We are awaiting a referral to see a Rad Onc, but this might take 2 more weeks to speak about the best way forward.

Upon diagnosis the onc also said they would restart Herceptin. This has now changed. They now don't want to restart Herceptin now because Perjeta Is only licenced in the UK to be used with Herceptin and Taxotere in first line treatment of secondary Breast Cancer. Basically is we start Herceptin now, we won't be able to use Perjeta in the future if needed.

We also discussed lapatinib plus capecitabine and they completely dismissed that it crosses the Blood Brain Barrier. We would of had to pay for this privately.

Annoyed is an understatement. Nearly 4 weeks has passed since surgery and nothing has happened.

Is there a timeframe in which a boost or WBRT must be done?

Originally we wanted to have a SRS boost to the area and save WBRT in case it was needed in the future. Now we're completely confused.

Any thoughts advice would be appreciated.

Thanks