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07-31-2007, 10:18 AM
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#1
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Senior Member
Join Date: Feb 2007
Posts: 27
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Taxotere side effects - hands
Once again I turn to all of you with a question. I completed 4 treatments of A/C previously and upon the advice of another oncologist, decided to do 4 of taxotere. The first one went pretty well. With the second round, my hands turned red, as if they had been sunburned, and peeled. I had my third treatment last Thursday, and although they decided to decrease my taxtotere by 15%, my hands are starting to show red again. Has anyone else had this and is there anything you can do that helps? My oncologist gave me some cream, biafine, but that is all I have been using so far. Thanks for any answers you may have. This has not been terribly painful, although it certainly looks terrible, so if there isn't anything I can do, I can certainly live with it. Always on the lookout for anything you ladies can offer though. God bless all of you.
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07-31-2007, 12:56 PM
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#2
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Deceased
Join Date: Oct 2005
Location: Chadds Ford, Pa
Posts: 206
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Hi Sheryl,
I did 7 taxotere last year and had nail issues, not specifically hands. However, someone on this site said to take bags of frozen veges to put across the nails during infusion to cut the blood flow to that area, and perhaps decrease side effects. Seems to me this might work with the hand issue too.
Good luck. Taxotere can be rough but the good news is once done things do return to normal pretty quickly.
Donna
__________________
Donna
Diagnosed 2/04 - Invasive ductal - no clean margins
node negative - er+pr+, her2++
Mastectomy 4/04 - 4 rounds AC
9/05 - mets to liver treated with carbo/ixabipelone/herceptin
3/06 - complete remission
9/06 - new liver mets, starting Taxotere/Herceptin
1/07 -Liver mets stable, staying on Herceptin
5/07 - Liver, lung progression - starting T/X
12/07 - Liver, lung progression - starting weekly Navilbene/Herceptin
4/08 - Liver progression - started Abraxane, Carbo, Tykerb and Herceptin
7/08 - Liver Progression - started Gemzar, Avastin and Tykerb
10/08 - Liver progression - starting Doxil
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08-01-2007, 09:54 AM
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#3
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Senior Member
Join Date: Sep 2005
Location: Maryland
Posts: 30
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This happened to my hands. By the 2nd round, it looked like I had a bad sunburn that was followed by peeling. It was quite uncomfortable. I recall that by the 6th or 7th round it started to reduce.
__________________
Margo
Diagnosed 08/2004 @ 45; Metaplastic Breast Cancer (MpBC)
Stage IV, HER2 3+, ER-/PR-, Met to Liver
08/2004 - Neo-adjuvant Taxotere/Carboplatin/Herceptin (TCH) - 4 rounds.
09/2004 - Herceptin - Weekly.
11/2004 - Liver RFA, followed w/TCH - 2 rounds.
12/2004 - Lumpectomy, axillary node dissection, followed w/TCH - 2 rounds.
05/2005 - Radiation - Breast, shoulder, neck (left side) - 35X
09/2005 - Developed severe osteoporosis - Boniva - monthly
04/2008 - Herceptin - Every 3 weeks (changed from weekly).
05/2012 - Mets: 3 new liver and 2 lymph nodes.
06/2012 - Start 16 rounds Navelbine and Herceptin weekly.
11/2012 - Liver resection, RFAs (8), lymphadenectomy (2), cholecystectomy.
12/2012 - Herceptin and Letrozole.
05/2014 - Mets: 5 aortocaval nodes & 1 mesenteric.
06/2014 - Herceptin/Perjeta/Taxotere - 6 rounds.
10/2014 - Herceptin / Perjeta - Open ended
04/2015 - Progression: Porta hepatic node, 2 aortocaval nodes.
05/2015 - Exploratory surgery treating progression, 12 nodes removed.
07/2015 - Restart Herceptin / Perjeta
01/2016 - Progression 8 nodes.
02/2016 - Starting T-DM1 (Kadcyla) - Open ended.
07/2017 - Progression.
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08-05-2007, 09:05 PM
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#4
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Senior Member
Join Date: Mar 2007
Location: Hilo, Hawaii
Posts: 1,867
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I had bright red skin under my hands and under my feet and would be exaserbated if exposed to heat. I had it come and go starting with my first chemo. I believe what we have is the Hand-Foot Syndrome which is a side effect of the chemo. It is caused by small amts of the drug leaking out of capillaries in the palms of hands and soles of feet. Exposure to heat and friction increases this leakage. Results can be redness, tenderness, and peeling. Can look like a sunburn.
Prevention can be to take a steroid such as decadron before chemo, day of chemo, and day after chemo. Also wear gloves when you wash dishes, watch the excercises that make a lot of friction (jogging, jumping, etc), no long hot showers, etc....
harrie (maryanne)
__________________
*** MARYANNE *** aka HARRIECANARIE
1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen
2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy
2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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08-05-2007, 09:18 PM
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#5
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Senior Member
Join Date: Mar 2007
Location: Hilo, Hawaii
Posts: 1,867
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hand/foot syndrome
Continuation on the hand/foot syndrome....
Cooling is suppose to help......ice packs on feet, bag of frozen peas may help.
Lotions: avoid,
Instead use emollients such as Aveeno, Lubriderm, Bag Balm. I used Aveeno and it felt great.
Tylenol for the discomfort;
__________________
*** MARYANNE *** aka HARRIECANARIE
1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen
2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy
2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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