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Old 10-02-2007, 07:38 PM   #1
Julie2
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Life can be sweeter if you cut out the sugar

http://news.yahoo.com/s/nm/20071002/...vity_sweets_dc
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Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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Old 10-03-2007, 02:50 AM   #2
R.B.
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Thank you very much for posting that. It is truly thought provoking.

This issue of the need to oxidation of sufficient strength to zap the baddies is intriguing.

It is back to that subtle need for balance again.


RB
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Old 10-03-2007, 06:57 AM   #3
Sandy in Silicon Valley
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The poor worms!!!

First glucose, then antioxidants - this cannot be a normal diet for worms!!! Why don't they leave the poor worms alone???!!! Where are the PETA protests???!!! And how many worm study findings are borne out in humans, who eventually become one of the natural feeding grounds for worms?

Plenaria (flatworms), fed the ground up remains of other plenaria which had been taught to negotiate a maze, were able to find their ways through the maze without further training.... This has provoked much controversy over whether human students would benefit from being fed the ground-up remains of their professors...

%%%giggles%%%
Sandy in Silicon Valley
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1992 - age 44/ ER-/PR+ Stage II dx - mastectomy, CAF x 6 cycles; Tamoxifen
1997 - BRCA1 mutation dx'd
1998 - ovaries removed
1999 - off Tamoxifen, on Arimidex
2003 - dx'd Stage IV - lymph nodes & lungs. ER-/PR-/HER2neu+++.
Tx: Herceptin & Taxotere (6 cycles).
2005 - 2.9cm x 3.6cm brain tumor. Craniotomy, CyberKnife. 9 mo. staph aureus infection at incision site - 2nd craniotomy. Two small brain mets CyberKnife'd.
2006 - revisit Xeloda - dosage lowered to 2500mg/day, 5 cycles.
2007 - "spot" dx'd on qtrly brain MRI - same location as CyberKnife 7/05. > by 2-4mm per quarter - - radiation injury or re-growing cancer? Tykerb added to Herceptin - July, still "watching & waiting". Otherwise, fully functional...


"The majority of people are not only afraid of holding a wrong opinion, they are afraid of holding an opinion alone." Kierkegaard
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Old 10-03-2007, 10:11 AM   #4
R.B.
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What interesting things worms are.

You could write a column. The underlying wit made me laugh. I do not know how the worms would feel about loosing their eventual meal of professors. Maybe thats how they get their intelligence.

More seriously are any of the effects at mitochondrial level applicable to mammals?. I had a quick search and maybe they are.

Respect to worms. May be we are not as distant from worms as we would like to think.


Ubiquinone is also called CoQ10

Clocked Out: Mice missing clk-1 die young (Mitochondrial respiration)

R. John Davenport
http://sageke.sciencemag.org/cgi/con...e;2001/10/nw38

"Previously, scientists identified a nematode gene, clk-1, that generates ubiquinone and limits life-span. New work suggests that mice lacking the corresponding gene display similar abnormalities as do worms: For example, they make unusually small amounts of ubiquinone and consume less oxygen than normal, although an effect on life-span has yet to be observed. The work opens up new avenues for studying the role of ubiquinone in mammals and might lead to insights into how ROS production influences aging."

Witty responses welcome.

RB
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