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12-11-2005, 10:16 AM
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#1
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Fertility Drugs Anyone???
I read a post that John submitted, and he said he felt that his wife being on fertility drugs may have caused the Breast Cancer.....made me think as I was on Clomid for 2 years and HCG shots for 1 year before becoming pregnant....then I had twins. Just curious how many on this board ever took fertility drugs and if in fact there may be a relationship.
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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12-11-2005, 04:59 PM
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#2
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Senior Member
Join Date: Dec 2005
Posts: 27
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Hi,
I am new to the group and reading through the postings. I took fertility meds to also get pregnant 11 years ago for several years and have also wondered if this was party the cause of my bc.
I was also blessed with twin girls because of my fertility treatments...but one has to wonder??
Kristen
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12-11-2005, 05:51 PM
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#3
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Junior Member
Join Date: Sep 2005
Posts: 4
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Count me in on the fertility drugs....for 6 years.
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12-11-2005, 05:54 PM
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#4
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Senior Member
Join Date: Nov 2004
Location: Henderson, NE
Posts: 413
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i took progesterone and HCG shots with 2 of my preg. but i have hormone neg breast cancer. I did think of that when i got breast cancer
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12-11-2005, 08:02 PM
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#5
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Michele
I am also Hormone neg.....but after all the HCG and Clomid (triple doses for a year), I wonder...I did have twin girls though, so no matter what, it was worth any risks.
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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03-14-2006, 01:02 PM
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#6
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Senior Member
Join Date: Sep 2005
Location: Grand Rapids, MI
Posts: 1,516
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Bump
xxxxxxxxxx
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03-14-2006, 01:18 PM
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#7
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Senior Member
Join Date: Jan 2006
Posts: 58
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I did.
My kids are all IVF babies, I had my oldest son in '99 and twin boys in '01. So I was on quite a few fertility meds throughout. Studies don't show any link between fertility drugs and breast cancer - if anything there is a slightly increased risk of ovarian cancer.
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03-14-2006, 01:31 PM
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#8
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Senior Member
Join Date: Dec 2005
Location: Norway
Posts: 58
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I didn't
Interesting thought. Might explain why BC increases in younger women. I have a daughter, but never used fertility drugs.
Toril
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03-14-2006, 03:43 PM
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#9
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Senior Member
Join Date: Feb 2006
Posts: 43
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I did 2 IVF's and lots of fertility meds..
and also have 2 year old twins. I am BRCA 2+ so I was pre-disposed, but I think the fertility drugs brought it on sooner than maybe it would have come. On my first IVF I argued with the OB to lower my meds because I was going to overstimulate and he only brought me down a bit, to which I totally overstimulated and my Estrogen levels were sky high! I think all that Estrogen and Progresterone floating around were not good, but as someone else said, my twins are amazing and I would not have done it any other way, just would have been much more on top of things when I felt the lump!
Natalie
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03-15-2006, 09:55 AM
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#10
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Senior Member
Join Date: Oct 2005
Location: Howell , Michigan
Posts: 40
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I did 4 cycles of clomid in 95, 3 cycles of follistim & progesterone in 98, and then another round of follistim in 2002 which ended up in the birth of my son. I was diagnosed when he was 18 months old. He is now 2 1/2. He is a great blessing to us, but I have felt the fertility drugs played a big part in developing breast cancer so early.
Michelle
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03-16-2006, 08:30 AM
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#11
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Guest
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Lupron
How many took Lupron during the fertility!
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03-16-2006, 10:45 AM
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#12
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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I did not...just Clomid and HCG injections.
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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03-16-2006, 04:05 PM
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#13
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Senior Member
Join Date: Sep 2005
Location: Central Valley, CA
Posts: 73
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I took progesterone during my first trimester.
Helen
__________________
- Diagnosed May 2005 8 months after giving birth. Stage IV due to a single liver mets.
- Carbo/Taxotere/ Herceptin combo for 6 months
- Herceptin/ Navelbine
- Recurrence on the same liver spot in 7/07
- Liver resection 9/07
- Tykerb/xeloda 10/22/07
- NED since 9/07 and continued Tykerb/xeloda
- PET/CT in May 2009 show small spot in lungs. Continued Tykerb/xeloda
- PET/CT in Aug 2009 shows progression on lung nodules (slightly bigger)
- Onc considering Taxol/avastin
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03-17-2006, 05:48 AM
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#14
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Senior Member
Join Date: Jan 2006
Location: Victoria, Australia
Posts: 95
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Very interesting to read your replies. I have always believed that my IVF treatment contributed to my BC. I did one stimulated round of IVF before my son was born 5 years ago. We then did another 3 stimulated when Mitchell was 2, and I was diagnosed when he was 2 1/2. All my doctors have been very careful with their wording, but each one has said that I was probably always destined to develop BC, however the IVF treatment probably brought in on much quicker. I know of another 3 women who have developed BC after IVF, and one who developed ovarian cancer.
In Aus, it has always bothered me that the only research has been done by the fertility clinics, and of course the results show that there is no link. I still don't understand why the clinics can't tell the patients to be more vigilant about their bodies, and to have regular mammograms.
I have often wondered thought that even if I had been told I had a 20% chance of developing BC after IVF treatment, I would have gone ahead anyway. Our son is the best thing that has ever happened to us, and I wouldn't give him back for anything.
Love Lisa
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03-17-2006, 08:09 PM
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#15
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Junior Member
Join Date: Feb 2006
Location: Doylestown, Pa
Posts: 1
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Yes, I took fertility drugs for two years (triple doses), also had throyid disease and polycystic overaian disease. I have felt that all this hormone inbalance may have contributed to geeting bc. Kathie
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