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Old 04-24-2009, 08:45 AM   #1
Shobha
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Join Date: Feb 2008
Location: Bayarea,CA
Posts: 679
Worried about not being given Tamoxifen

Hi,

I am getting concerned that I was never given tamoxifen. Granted I am only weakly ER+ (~10%) but since I am premenopausal, it makes me nervous. I am taking Evista for osteopenia, which is supposed have similar benefits as Tamoxifen.

Can you please give me your opinions? Or, if this has been already discussed before, point me to the thread?

hugs,
shobha
__________________
DX: 06-30-2007 - left breast -stage IIIB, Her2/Neu 3+++, ER weakly positive, PR-
Taxol+herceptin weekly for 3 months
FEC+herceptin every 3 weeks for 3 months
BRCA 1 and 2 - Negative
Jan 2008 - Bilateral mastectomy, prophylactic Rt. side.
Radiation for 5 weeks
Completed my yr of herceptin on 07-14-2008
Brain MRI - 3/2/09 Clean
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Old 04-24-2009, 10:07 AM   #2
Becky
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Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
Dear Shobha

The trial below only compared Evista to Tamoxifen as a bc preventative in high risk women but it prevented cancer head to head against Tamoxifen with far less side effects.

A nine year bc survivor at my local support group took Evista instead of Tamoxifen because she had a blood clotting problem (another condition) and couldn't take Tamoxifen so the onc tried this.

I think the 2 drugs will give similar results in preventing mets or recurrences its just the studies aren't out there yet. But results in preventation are and the 2 drugs act the same.

Secondly, you would never be permitted to take both drugs at the same time.

I hope this helps and eases your mind as you ARE doing something about that estrogen receptor after all.



http://www.cancer.gov/STAR
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 04-27-2009, 09:22 AM   #3
Shobha
Senior Member
 
Join Date: Feb 2008
Location: Bayarea,CA
Posts: 679
Becky, thanks so much! This does put my mind to rest. It is so much easier and faster to get answers to my worries here than any of my doctor's offices!

So grateful,
shobha
__________________
DX: 06-30-2007 - left breast -stage IIIB, Her2/Neu 3+++, ER weakly positive, PR-
Taxol+herceptin weekly for 3 months
FEC+herceptin every 3 weeks for 3 months
BRCA 1 and 2 - Negative
Jan 2008 - Bilateral mastectomy, prophylactic Rt. side.
Radiation for 5 weeks
Completed my yr of herceptin on 07-14-2008
Brain MRI - 3/2/09 Clean
Shobha is offline   Reply With Quote
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