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Re: TDM-1 side effects
Hi Nancy and others!
I started t-dm1 last week in Stockton as well. I would have to say my first dose side effects were INTense. I was not expecting this. I've been on the chemo merry go round for years, and this was one of the hardest ever to go through.
I was knocked out for five straight days - today is my first day up. I have mets in the liver - within 2 hours of infusion, it felt like my liver swelled alot, pressed on my stomach and stayed that way until yesterday. So, 4-5 days. Something is still pressing, but not as much.
I was very, very weak - unable to support my own weight. Vertigo at night and am from days 3-5. Strong headaches days 1-5.
I feel much better today, and too hope this is a good sign. I haven't heard of anyone having s/e's like this on tdm1. I will let the trial people know - but wanted to ask here as well.
I, too, felt like it means it working. For me, it felt like I had literally ingested a poison with this first dose of tdm-1.
Did anyone else get any s/e's close to this?
Thanks -
Kim
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Dx Stage 3C 2005, triple +, tons of lymph nodes as well. FEC, surgery, TCH, rads, herceptin 1 year. And, Aromasin.
2007 - recurrence to medistinal lymph node, Abraxene and Herceptin - took it down 50%
2008 - on Arimidex/Herceptin - stable lymph node.
2009 - stable on Arimidex/Herceptin
2010 - lymph node progression and liver mets.
2010 - went on Gemzar, Navelbine, Herceptin - Navelbine and Herceptin took liver mets down. lymph node slightly progressed.
2010 - did Xeloda & Tykerb - MAJOR progression in liver in only 6 weeks.
Dec 2010 - present - Ixempra/Avastin/Herceptin/Fasoldex - regressing
June 2012 - chemo break
Sept 19, 2012 - start t-dm1. Chose this over going back on Ixempra.
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