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Old 01-15-2013, 09:19 PM   #1
A. L. Pendley
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Join Date: Jul 2012
Posts: 14
Re: Starting WBR for brain metz

Good to read about others going thru whole-brain radiation. I haven't included my history yet (need to) ----
DX 1999, went thru usual A/C/T
NED until 2004 - then mets to lungs.
Went in/off of Herceptin, Tykeeb, Xeloda, Zometa, Xeloda. Most recently was in Geron+Herceptin+paclitaxel study in Denver but got kicked out due to new brain met.
I did SRS (cyber knife) 2 times - each time got 2 tumors fairly successfully. But due to concerns of tumors crossing into meninges, we're considering whole-brain radiation next month. I did go back on Tykerb with the Herceptin and Xgeva. I run a small business and work 50 hrs a week, so I'm concerned, but optimistic. I'll look at the others' posts for clues!
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Old 01-15-2013, 09:24 PM   #2
dchips1
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Join Date: May 2006
Location: Mesa, Az
Posts: 219
Re: Starting WBR for brain metz

look at some of the posts for using Intrathecal Herceptin, alone and some are taking it with Topetecan as well.

Good Luck to you
Darita
__________________
dx 1/06 IDC 2cm 38 at dx
2/06 L mast nodes 3/9+ SNB neg ER-/Pr - her2 + Stg 4 liver/pelvis
3/06-9/06Taxol/Carbo/zometa/Herceptin
3/07 6 brain mets WBR down to c-2
4/07 osteonecrosis jaw
1/08 mri new 9mm lesion right lower side
2/08 gamma knife 1 lesion 11/08 regamma
10/09 latent rad necrosis to brain met,
1/20/10 crani: lesion necrosis w active cells continue her add tykerb
1/11 NED just Ingrown toenail! YEAH GOD
8/11 Tykerb, herceptin weekly, elevated her2 levels, negative scans
oct -march 11 new neuro deficits lower legs
3/12 2 spinal metsTykerb, Herceptin
04/12 4050cGY rads T 2-4 & T7-9
5/12 Brain,cervical lumbar clear/thoracic slight decrease
10/12 t 2-4 shrunk t-9 grew start Xeloda, 02/13 stop xeloda,5/13 on metformin, decadron, Tykerb, iv and IT herceptin 5/30/13 total #11 #2 of 80mg dose weekly.
9/13 100mg of IT her, IV hern, 750 mg tykerb, 3mg dec.
last Mri T--3 SHRUNK t7-9 shrunk no edema. Left shift in CBC bone marrow BX negative.
10/13 Ct has shown Double left ureters with stones/cysts in them, after 3 births and lots and U/S iit takes cancer to figure out you have 2 smaller ureters going into 1 kidney!
12/13 Mri brain no new lesions, cervical and lumbar arthritis.
Tspine lesion at T3 stable, T 7-9 GROWTH lots of pain

1/29/14 HIHO HIHO its off to Neuro surgery I go





Life is Good when you wake up in the morning and take a breath and know that God has given me another day.


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