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Old 09-03-2009, 07:08 AM   #1
Jaimieh
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Join Date: Mar 2009
Posts: 126
Herceptin and wound issues ??

I finished 6 rounds of TCH on May 18 and I had exchange surgery on June 17 and I have been having wound healing problems since. Initially the incisions close and then after I get herceptin they open back up in the same week. My implants where exchanged 3 weeks ago yesterday and everything was fine during my follow up on Tuesday with the PS. Wednesday morning I woke up to a tiny blister on my incision and today there is a hole. During my second exchange all of the fluid was checked and it isn't an infection. So it got me thinking is it something to do with the herceptin ?? (which I will continue with until February) I am really concerned now that I will have incision problems even if they remove the implants.

So did anyone else have healing problems while on herceptin ??
__________________
Diag. 12/24/08-
IDC 1.3 er-/pr- HER2+
Grade 3 0/2 lymph nodes
no angiolympathic invasion

Bi-Lat. Mast. 1/8/09
Exchange scheduled for 6/17/09
Lost implants due to unknown reason :(

Hip Flap 1/26/2010 in NOLA :) LOVE EM'

TCH x6 (6 done and I am hoping to never do it again )

Well so much for never...
Local recurrence May 25,2014 is left over breast tissue.
April 2 , 2014 lumpectomy
April 28, 2014- June 9, 2014 start AC x 4
Taxol x12
Perjeta x 6
Herceptin x 18
And 33 rads just for fun. NOT!!!
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Old 09-03-2009, 07:46 AM   #2
Joan M
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Join Date: Oct 2007
Posts: 1,851
Re: Herceptin and wound issues ??

Jaimieh,

I've had several two surgeries (and radiofrequency ablation of the lung, where my lung collapsed during the procedure and I had to stay in the hospital for a few days with a drainage tube), and I have not had healing problems with Herceptin.

Joan
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Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
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Old 09-14-2009, 01:50 PM   #3
rondo
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Join Date: Dec 2008
Location: Monterey County, CA
Posts: 37
Re: Herceptin and wound issues ??

Jamieh,
I did have some problems with recurrent wounds on my fingers in areas of repeated trauma; they recurred after every herceptin treatment. The one surgery I had during herceptin healed, but there was a lot of swelling and nerve pain. All of this did eventually resolve, and I am nearly 3 months past my last herceptin treatment. I had my port out 2 weeks ago today, and am healing up like my normal self again. I do think the herceptin definitely affects healing and drags you down a bit, but it all went away for me and I am feeling GREAT so hang in there!
__________________
IDC 6 mm l.b. 3/08 age 49; ER <1%+; PR -; KI67 40%; HER2 +++by FISH; lumpectomy/snb 4/08; extensive dcis found at surgery (didn't show in bx or mammo); micromet in sn; MRI breasts and chest 4/08-NED; re-excision l.b. 5/08; refused axillary node dissection; no ca found in re-excision tissue. TCH q 3 wk x 6 finished 10/08; whole breast rad x 7 wk finished 12/08; refused axillary and supraclavicular rad. Herceptin thru 6/09. Refused tamoxifen & aromatase inhibitors.
1/13 so far so good:-) have vestibular hypofunction from chemo but its all good since now officially on borrowed time!
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