how fat in your diet may influence whether cancer metastasizes

[Lani]

http://news.uns.purdue.edu/x/2009a/0...Fatcancer.html

[mts]

Excellent article--- Thank you for posting !

[Christine MH-UK]

"The researches used the imaging and cell-counting tools to document that linoleic acid, which is predominant in polyunsaturated fats, caused increasing membrane phase separation, whereas oleic acid, found in monounsaturated fats, did not."

At the risk of taking R.B.'s job, this would indicate that linoleic acid, an Omega 6, might be quite bad.

Interesting about oleic, too, given Menendez's work on fatty acids which suggests that oleic acid might be beneficial against her-2 breast cancer and herceptin-sensitizing.

[karen z]

Thanks very much for posting this.
kz

[RobinP]

This supports prior studies that have said the same thing. In the WINS, a high fat diet promoted hormonal negative bc relapse.

[jones7676]

Great info - thanks so much!

[AlaskaAngel]

.... then (for me at least) it raises the question yet again about the standard, unquestioned continuing use of some drugs in support of chemotherapy.

We already know that the steroids used in support of chemotherapy cause significant weight gain for many (but not all) cancer patients. This is weight that is then harder to lose because chemotherapy puts many patients in menopause. Metabolism in menopausal patients is lower and the recommendation is for those menopausal patients who are overweight to "get used to" permanently eliminating somewhere between 200 and 400 calories a day from what they've been normally eating just to maintain and not gain more weight. Adding exercise to that permanent sacrifice is recommended for losing some of the excess weight gained during chemotherapy.

So, in looking at this logically as a cause and effect situation.... and knowing that there is a significant population of breast cancer patients who would never need any chemotherapy at all to remain NED.... (particularly now that most breast cancer is being diagnosed in the early stages)... and knowing that having the chemotherapy includes being given the steroids... it is logical for me to ask, how many of these people are having recurrence DUE TO the supportive drug given with the chemotherapy that often causes significant weight gain?

Considering that a large number of the population is overweight even before treatment with these drugs, how many patients are among us who might have been able to avoid recurrence with mets entirely by not having the therapy that involves the use of these drugs?

[R.B.]

Thanks Christine,


Do you have a name or link for the paper. I would be fascinated to see it.

I meant to look for it but have not had the time, and the focus has been low.

I had an abscess surgically removed from my jaw that had persisted from an asymptomatic tooth death I guess some years ago. Treatment and root filling did not solve the issue. Finally an unarguable lump appeared and a jaw abscess was diagnosed.

I have been complaining about spread to the upper sinuses, skin problems, not feeling good, sleep loss, anxiety, bad tastes in mouth etc, but was largely greeted with blank looks, and had the satisfaction of telling them that the residual bleed from the surgical removal had appeared in the back of the nasal tract / back of the throat rather than the mouth where you would expect it, which unless I have spontaneously evolved the ability to transport matter would suggest the abscess had made a drain to the sinus area (-:.

The moral of which is if you have a heavily filled tooth that goes a little loose do not ignore it (-:

[DanaRT]

Thanks for the article. Gives me incentive to put the slice of pizza in the trash...