I start this trial on Monday, July 26, 2010. I got word today that I am in the group that will get a year of Tykerb with no Herceptin, which is a little scary.
I have IDC, with negative sentinel node biopsy, tumor size 1.8 cm. I had a lumpectomy and re-excision with clean margins. This makes it a Stage 1 cancer.
I am PR+ ER+ and Her2neu+++, with a Bloom Richardson cell grade of 3 (score of 8 of 9).
The other thing that is a little scary is that it appears that Tykerb is harder on your liver than Hrceptin. I have non-alcohol related fatty liver, with AST 37 and ALT 61. (I know those are a little high, but do not really know how high, risks, etc...)
I have "chemo class" tomorrow and will be able to talk to the clinical trials coordinator and oncologist then and may get some more information. Any insight appreciated. I was delighted to find this thread.
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Rachel
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Re: ALTTO Trial - Herceptin / Tykerb
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