HonCode

Go Back   HER2 Support Group Forums > Articles of Interest
Register Gallery FAQ Members List Calendar Search Today's Posts Mark Forums Read

Reply
 
Thread Tools Display Modes
Old 02-05-2005, 02:35 PM   #1
Christine MH
Guest
 
Posts: n/a
c-erbB-2 expression and nuclear pleomorphism in canine mammary tumors

I just found it interesting that dogs apparently get HER2 breast cancers just like humans do. Maybe this will help scientists figure out more about Her2 sooner.

Brazilian scientists report that
"the morphology and biology of canine mammary
malignant tumors are closely linked, just as
in human breast cancer. Therefore, these
results reinforce the idea that spontaneous
canine mammary tumors can be used as a
model to study the mammary carcinogenic
process and may be relevant to the study of
human breast cancer (36-38).
The expression of immunoreactive cerbB-
2 in canine mammary tumors could be
an important factor in canine mammary carcinogenesis.
In humans, c-erbB-2 expression
has been implicated in the initiation of
breast cancer, and has even been used as an
oncogene-targeted therapy (39,40). This fact
opens up the possibility of using anti-c-erbB-
2 antibodies for the treatment of canine mammary
tumors. In addition, further investigation
is necessary to assess the value of the cerbB-
2 marker as a predictive factor in mammary
cancer."
  Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On

Forum Jump


All times are GMT -7. The time now is 12:27 PM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2024, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007 - 2021
free webpage hit counter