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06-19-2007, 05:17 AM
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#1
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Senior Member
Join Date: Nov 2004
Location: Olathe, KS
Posts: 107
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Can herceptin be used for her2-??
Is there any evidence at all that herceptin can be used for those that are considered her2-? What about only weakly positive? If so, where is the cut-off? Just asking for a friend.....the theory is that we all have her2 genes, but wouldn't it work even if the overexpression was not as strong?
Any articles or studies?
TIA! You ladies ROCK!
Rose
__________________
Rose
Dx'd 1/04 at 33, while 33 weeks pregnant
Dx: Stage IIIC IDC, ER-, PR+ (23%), Her2=2.7 (IDC)/7.6 (FSH), 2.5cm primary tumor, grade III, 11/18+ nodes (largest 3.8 cm)
Treatment: A/C *4, T *4, 1 year of herceptin (BCIRG 006), mastectomy, rads (7 weeks), zoladex (5 years) with tamoxifen (2 years)/aromisin (3 years), bilateral SGAP summer 05 at NOLA
Oops, retested tumor and I guess I'm er/pr- after all.
Stopped all hormonal tx 10/07. Periods resumed 6/08. Bye bye hot flashes!!!!
http://www.edrie.com/kopecky
*~VISIT OUR FAMILY!~*
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06-19-2007, 07:42 AM
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#2
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Senior Member
Join Date: Sep 2005
Location: Grand Rapids, MI
Posts: 1,516
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Rose...
I know they are studying where the "cutoff" should be. I know I am weakly positive 3.16 FSH and I had Herceptin. Here's an article and I will see if I can find any current studies. Take care and God bless.
Rhonda
http://www.nytimes.com/2007/06/12/he...ml?ref=science
__________________
Rhonda
Dx 2/1/05, Stage 1, 0 nodes, Grade 3, ER/PR-, HER2+ (3.16 Fish)
2/7/05, Partial Mastectomy
5/18/05 Finished 6 rounds of dose dense TEC (Taxotere, Epirubicin and Cytoxan)
8/1/05 Finished 33 rads
8/18/05 Started Herceptin, every 3 weeks for a year (last one 8/10/06)
2/1/13...8 year Cancerversary and I am "perfect" (at least where cancer is concerned;)
" And in the end, it's not the years in your life that count. It's the life in your years."- Abraham Lincoln
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06-19-2007, 09:25 AM
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#3
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Senior Member
Join Date: Apr 2007
Location: Mississippi
Posts: 600
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her2- and benefits of herceptin
I put this link in my post 'new info on herceptin" It adresses your question. I tried to rename the post but couldn't.
http://www.nytimes.com/2007/06/12/he...MrP6WGbWrQjucA
Leslie |
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06-19-2007, 06:39 PM
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#4
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Senior Member
Join Date: Nov 2004
Location: Olathe, KS
Posts: 107
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Thank you! Exactly what I needed. I'm heading to ASCO's site now.
__________________
Rose
Dx'd 1/04 at 33, while 33 weeks pregnant
Dx: Stage IIIC IDC, ER-, PR+ (23%), Her2=2.7 (IDC)/7.6 (FSH), 2.5cm primary tumor, grade III, 11/18+ nodes (largest 3.8 cm)
Treatment: A/C *4, T *4, 1 year of herceptin (BCIRG 006), mastectomy, rads (7 weeks), zoladex (5 years) with tamoxifen (2 years)/aromisin (3 years), bilateral SGAP summer 05 at NOLA
Oops, retested tumor and I guess I'm er/pr- after all.
Stopped all hormonal tx 10/07. Periods resumed 6/08. Bye bye hot flashes!!!!
http://www.edrie.com/kopecky
*~VISIT OUR FAMILY!~*
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