No anti-tumor effects seen in adding Zolendraic acid to chemo

[Hopeful]

Abstract:

http://www.abstracts2view.com/sabcs1...u=SABCS10L_236

Poster:


http://www.abstracts2view.com/sabcs1...hp?nu=P1-11-01

Hopeful

[Rich66]

Hmmm...maybe according to the lab metrics used. But it might be good to try more than one dose and see how the tumor responds.

Conclusions: No definite evidence of a direct anti-tumour effect of the addition of Z to CT was observed, but potentially relevant biological effects were seen in this small study. The clinical relevance of recovery of cell turnover by D21 with CT+Z is unclear. Studies with more frequent dosing of Z are warranted to exploit any potential anti-angiogenic effect of Z.

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