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Old 03-24-2006, 01:12 PM   #1
Lani
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More On Flaxseed And Its Components

LIMITATIONS:1)IN MICE 2) NOT SPECIFICALLY FOR HER2+ BREAST CANCER

ABSTRACT: Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice [Cancer Letters; Subscribe]
This study determined the effect of 10% flaxseed (FS) and its components, secoisolariciresinol diglycoside (SDG) and flaxseed oil (FO) alone or in combination (SDG+FO), on the metastasis and recurrence of human breast tumor after excision in nude mice. Mice were injected orthotopically with human breast cancer cells (MDA-MB-435) and fed basal diet (BD). When the tumors reached an average size of 110 mm2 (0.9 g), surgical excisions were performed, and the mice were assigned to one of five diet groups for 7 weeks. The total incidence of metastasis was significantly lower in the FS, SDG, and SDG+FO groups. Reduced lung and lymph node metastases were observed in the FS and SDG+FO groups. In the FS and FO groups, a greater reduction in lung and total metastases was found when excised tumors were ?0.9 versus >0.9 g. There was no significant difference in tumor recurrence among groups. In conclusion, FS and its components inhibited tumor metastasis but not tumor recurrence after surgical excision of the primary tumor.
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Old 03-24-2006, 02:19 PM   #2
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Tumor metastasis inhibition is good!

Another interesting post

Thanks RB
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Old 03-25-2006, 06:42 AM   #3
DeborahNC
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After my initial BC in 2003 I began 2400mg FO daily. Perhaps that prevented any mets when I recurred locally last year.
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Old 03-25-2006, 09:19 AM   #4
cherylynnie
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Question

Deborah,


How much of the flaxseed oil do you take daily?

I have some but haven't started taking it yet.

Thanks!
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Cheryl
Stage II, Grade III, ER+/PR-, Her2 3.0 amplified, N 0/5, dx 9/05, 39 yrs
Right Mastectomy, immediate tram flap reconstruction
4 AC, 4 Taxotere finished 3/15/06
Currently on Herceptin and Tamoxifen
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Old 03-25-2006, 01:36 PM   #5
DeborahNC
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Cheryl,

I'm still taking the 2400mg in caps and eat a tablespoon of flax seed on my cereal each morning. I tried opening the caps and mixing it in cottage cheese as recommended in the Budwig diet, but that made me absolutely gag! The seeds actually have a nice taste, but I understand they're loaded with calories.
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Old 03-25-2006, 03:19 PM   #6
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Cherylynnie - Try the search option above RH corner. There are lots of posts on flaxseed, how to take etc, options etc

RB.
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