I do not have access to the full trial and am unable to understand the implications of this. As usual I came this on whilst looking for something completely different.
Can somebody translate this with more certainty? Are "homozygous wild-type carriers" the general population?
IF they are this trial seems to be suggesting alchohol intake does increase the risk of BC.
More questions!!
RB
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum
Peroxisome profilerator-activated receptorgamma2 Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes.
Vogel U, Christensen J, Nexø BA, Wallin H, Friis S, Tjønneland A.
National Institute of Occupational Health, Copenhagen, Denmark.
Abstract.
"Alcohol consumption was associated with a 1.21-fold increased risk of breast cancer per 10 g alcohol/day (95% CI=1.06-1.35) among homozygous wild-type carriers, whereas alcohol was not associated with breast cancer risk among variant allele carriers (P for interaction=0.005)."
Threaded Mode