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Old 10-07-2007, 01:30 PM   #1
sally
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taken off tykerb
Well I have been on Tykerb/xeloda for about 6 weeks and had to take a break due to side effects. I am not sure if there is going to be a change of drugs or alter the dose of the t/x. I will find out on Tuesday what the new plan is. Just thought I would share. Take care. Sally
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Old 10-07-2007, 03:42 PM   #2
Esther
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Sally, depending on the severity of your symptoms, you might discuss lowering your tykerb to 3 pills a day, and Xeloda to 2 twice a day.

Hope you feel better soon!
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Old 10-07-2007, 04:44 PM   #3
chrisy
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Sally,
Many people have to have the Xeloda reduced, and some have had the Tykerb reduced, so it is definitely a viable option to discuss w/ your doctor.
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June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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Old 10-10-2007, 06:18 AM   #4
Lala
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Hello Sally,
I had to take a break after my first round of Xeloda Tykerb.
I have had both doses lowered. I take my Xeloda 1 week on 1 week off now; this has helped with keeping my energy up. I Wish you the best.
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