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Old 08-31-2012, 12:21 PM   #1
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Unhappy Oh yeah, and about that bad leg...

Hi all,*
I never posted news about the MK2206 trial running out of steam for me, nor about the persistent leg injury (torn muscle/tendon in leg which over the past weeks, and past few days has grown increasingly alarming.

The trial failure, Perjeta issue and interim plans were to be the main topics of discussion at my office visit with Dr Rugo yesterday morning.

So the NP and Dr Rugo took one look at my leg and the acute issue is that, whether it is a blood clot (now ruled out) or an infection around the injury. Either thing lands me in the hospital with an IV drip. *Now we know it's an antibiotic to,hopefully fight the infections, plus a unit of blood just for kicks.*

Well the day took a major turn and has now ended up as a Labor Day weekend at the always luxurious UCSF Parnassas hospital! *Actually, this is the best place for me to be, one of the best hospitals in California.

I just hope I don't have to listen to a timeshare presentation. *

But it's probably a several day ( or more) stay.

I believe this is a blessing, not *even disguised. *I knew there was something terribly wrong with the leg; now I feel there is a competent team looking at it from all the necessary angles...or maybe angels. * No way I could have pulled that together. *

I am an interesting and unusual case (go figure!) and have already had 6 doctors/surgeons looking at it trying to figure out what to do. *More on the way, too. They are trying to decide whether or not do do surgery to clean out some of the fluid/blood/infection. And have me NPO which is Latin for no putting anything in your mouth.

So i hope they decide soon, although the surgery sounds scary and painful, too.

I've recently relearned from a dear friend how powerful prayer can be...so am boldly asking for as many as can be floated out there...

Thanks for the love, my friends
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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