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04-25-2020, 02:48 PM
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#1
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Senior Member
Join Date: Mar 2006
Posts: 1,843
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Re: Coronavirus - is low vitamin D a factor - vitamin D and respiratory conditions
https://www.bmj.com/content/369/bmj.m1548/rr-6
'COVID-19 ’ICU’ risk – 20-fold greater in the Vitamin D Deficient. BAME, African Americans, the Older, Institutionalised and Obese, are at greatest risk. Sun and ‘D’-supplementation – Game-changers? Research urgently required.
Pleased to share another letter to the BMJ (The English equivalent of the NEJM) this time coauthored with 30 others, and structured around a pre-print examining vitamin D levels in hospital COVID-19 patients in relation to seriousness of condition.
Still, with others, trying to get more such studies looking at vitamin D levels in COVID patients and outcomes. Cheap inexpensive and easy and relatively quick to do . . . but requires the will and funding . . .
Acceptance of simple solutions, that may involve a little embarrassment have historically always taken many years
Hopefully in a more connected world we can do better, and take the necessary steps to determine if Vitamin D deficiency is indeed a significant factor in COVID-19.
An example - washing of hands for infection spread control took more than 20 years to gain acceptance and the proposer Semmelweis got put in a mental asylum for his attempts to get the message out
E.g. Washing hands before delivery of babies
https://www.upworthy.com/women-were-...igured-out-why
https://en.wikipedia.org/wiki/Ignaz_Semmelweis
" Women were dying from childbirth at hospitals. This 19th-century doctor figured out why. "
Doctors were doing autopsies and then attending births without washing hands or instruments. Semmelweis worked out that this was the problem and order washing with chlorine based disinfection and it worked - mortality was greatly reduced but . . .
"Unfortunately, the Semmelweis' colleagues did not embrace his findings — they were outraged at the suggestion that they were the cause of their patients' deaths. Semmelweis was fired from the hospital and eventually committed to an asylum. He died at the asylum two weeks later. (Several historians believe that he died, after being beaten at the asylum, from sepsis — an infection in the bloodstream caused by germs.)
" It would take about 20 years before his ideas would start to be accepted by the medical community. And even then, it was "germ theory" — and the work of Louis Pasteur in the late-1860s — that really convinced anyone of the importance of hygiene and handwashing."
Last edited by R.B.; 04-25-2020 at 02:56 PM..
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05-14-2020, 12:33 PM
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#3
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Senior Member
Join Date: Sep 2005
Location: Alaska
Posts: 2,018
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Re: Coronavirus - is low vitamin D a factor - vitamin D and respiratory conditions
Hi Everybody
Still firmly taking my vitamin D (thanks, RB!)
https://scitechdaily.com/vitamin-d-d...change-advice/
__________________
Dx 2002 age 51
bc for granny, aunt, cousin, sister, mother.
ER+/PR+/HER2+++, grade 3
IDC 1.9 cm, some DCIS, Stage 1, Grade 3
Lumpectomy, CAFx6 (no blood boosters), IMRT rads, 1 3/4 yr tamoxifen
Rads necrosis
BRCA 1 & 2 negative
Trials: Early detection OVCA; 2004 low-dose testosterone for bc survivors
Diet: Primarily vegetarian organic; metformin (no diabetes), vitamin D3
Exercise: 7 days a week, 1 hr/day
No trastuzumab, no taxane, no AI
NED
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05-14-2020, 04:16 PM
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#4
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Senior Member
Join Date: Mar 2006
Posts: 1,843
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Re: Coronavirus - is low vitamin D a factor - vitamin D and respiratory conditions
^ if you read my paper from 23rd March you may notice a certain resemblance in terms of content and posit.
https://www.mitofit.org/images/e/ec/...fit_200001.pdf
"The COVID-19 virus emerged in 2019. Mortality rates as at 20th March 2020 are much higher in southern than northern Europe. The elderly, and those with pre-existing conditions, are at greatest risk. It is hypothesised, vitamin D deficiency may significantly compromise, respiratory immune response function, thus greatly increasing risk of COVID-19 hospitalisation, severity and mortality. Winter vitamin D levels: based on; limited data, including; historical measured regional vitamin D deficiency rates (<25nmol/L), intakes, and plasma vitamin D levels; fortification and supplementation policies; and public vitamin D awareness: appear to be significantly lower in southern, than northern Europe. In respiratory system conditions, such as influenza, vitamin D has wide-ranging and fundamental roles, including through: gene transcription via COVID-19 relevant VDR (Vitamin D Receptor) pathways; ACE1 and ACE2 pathways; wider immune function; airway epithelial cell tight-junction function and integrity; and mitochondrial related, energetics, apoptosis and inflammation, management. Studies suggest vitamin D supplementation may be protective against respiratory conditions, in ‘D’ deficient persons. Would vitamin D supplementation of the deficient, mitigate the severity of the current COVID-19 outbreak; and reduce future, likely upcoming, seasonal amplification effects?"
Media Coverage / credit received by my paper = Zero
Citation of my paper in the above - nope
Depressing
Last edited by R.B.; 05-14-2020 at 05:03 PM..
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