 |
09-16-2008, 11:50 AM
|
#1
|
|
Senior Member
Join Date: Oct 2007
Posts: 18,946
|
Gene variation raises Melanoma risk
A gene variation known as cyclin D1 may raise a person's risk of melanoma by up to 80 percent, a new study has shown.
More... |
|
|
|
10-10-2008, 01:25 PM
|
#2
|
|
Senior Member
Join Date: Aug 2007
Location: Newport Beach, CA
Posts: 161
|
Thanks "News"
Hi News,
I am so glad you posted this as I was just diagnosed with melanoma in situ this week and I am a bit bummed. Next week I'll have a wide local excision.
Is it fairly easy to get a "genetic profile" as mentioned in the article?
Really appreciate your post,
Vicki Z
__________________
Diagnosed 12/03 at age 53
1.5cm tumor, ER-PR-, Her2 3+(rt side)
Stage 1B, Three negative nodes from Sentinel Node Biopsy
Paget's of the nipple, Infiltrating Ductal Carcinoma and DCIS of the rt breast
Bloom-Richardson score 8/9, P53+ 60-70%, Ki-67+ 30-40%
Skin-sparing mastectomy with immediate lat-flap reconstruction and saline implants, 1/04
Chemo: FAC, five sessions every three weeks Feb.-May 04, then switched to HTC weekly for 12 weeks, June-Aug 04
Zometa every 6 months for osteopenia, started April 09
|
|
|
|
|
10-20-2008, 08:02 PM
|
#3
|
|
Member
Join Date: Sep 2006
Posts: 14
|
This is so interesting. I have had 3 stage 1 Melanomas and 1 insitu melanoma over last 5 years. I was diagnosed with stage 2 breast cancer almost 3 years ago. I am BRCA 2 positive and my doctors have told me with that genetic mutation they do see families with melanoma as well. My two sisters also carry the BRCA gene mutation one got breast cancer at 31, I was dx at 36 but my other sister is 37 and still no breast ca. She had bilat. mastectomy after my dx. Anyway neither of them has had any skin problems. How easy is it to get this test I wonder? Are you brca positive? Melissa
|
|
|
|
|
10-22-2008, 11:51 AM
|
#4
|
|
Senior Member
Join Date: Aug 2007
Location: Newport Beach, CA
Posts: 161
|
Great info. Wonder what we can do with it?
Hi Melissai,
I think I tested negative for the brca 1 and 2. My father had a melanoma on his back in 1988 and he turned 80 this past year, so it has been 20 years for him.
Even though mine is "in situ," and stage 0, I am still a bit concerned, because it is an aggressive cancer as her2 is shown to be also. Catching it early is the key and I'm glad I did.
This all made me wonder how people with tattoos would ever find a melanoma on their skin.
Be well and enjoy your October,
Vicki Z
__________________
Diagnosed 12/03 at age 53
1.5cm tumor, ER-PR-, Her2 3+(rt side)
Stage 1B, Three negative nodes from Sentinel Node Biopsy
Paget's of the nipple, Infiltrating Ductal Carcinoma and DCIS of the rt breast
Bloom-Richardson score 8/9, P53+ 60-70%, Ki-67+ 30-40%
Skin-sparing mastectomy with immediate lat-flap reconstruction and saline implants, 1/04
Chemo: FAC, five sessions every three weeks Feb.-May 04, then switched to HTC weekly for 12 weeks, June-Aug 04
Zometa every 6 months for osteopenia, started April 09
|
|
|
|
|
10-28-2008, 10:33 AM
|
#5
|
|
Senior Member
Join Date: Aug 2007
Location: Newport Beach, CA
Posts: 161
|
To Melissai
Hi Melissai,
I just realized I didn't get tested for BRCA, but plan to see a genetic counselor. Is this a blood test? Just wanted to correct what I'd said before as I saw my oncologist and she said that I hadn't been tested for it.
See you online,
Vic
__________________
Diagnosed 12/03 at age 53
1.5cm tumor, ER-PR-, Her2 3+(rt side)
Stage 1B, Three negative nodes from Sentinel Node Biopsy
Paget's of the nipple, Infiltrating Ductal Carcinoma and DCIS of the rt breast
Bloom-Richardson score 8/9, P53+ 60-70%, Ki-67+ 30-40%
Skin-sparing mastectomy with immediate lat-flap reconstruction and saline implants, 1/04
Chemo: FAC, five sessions every three weeks Feb.-May 04, then switched to HTC weekly for 12 weeks, June-Aug 04
Zometa every 6 months for osteopenia, started April 09
|
|
|
|
Posting Rules
|
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
HTML code is Off
|
|
|
All times are GMT -7. The time now is 04:51 AM.
|
Linear Mode
