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Old 08-30-2006, 09:42 PM   #1
romo9
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HRT and HER!

Just found out that I have osteopenia in my back despite having "normal" Hip density. As I exercise ALOT and have sufficient calcium etc I am wondering about HRT if you are purely HER+++? Does anybody know? Many thanks ROMO
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Old 08-30-2006, 10:30 PM   #2
Cheryl E
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Yes, the HRTs do cause bone loss. Also, chemo can cause temporary bone loss as well. My onc. says it levels out 2 1/2-3 years after you stop chemo and start on the HRTs.
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Old 08-30-2006, 11:35 PM   #3
tousled1
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I was on HRT before I was diagnosed with breast cancer. As soon as the diagnosis was confirmed, my oncologist took me off my HRT.
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Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
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Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
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Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
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March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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Old 08-31-2006, 02:33 AM   #4
romo9
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Thanks Its just that a friend said that there was now a new one on trial that is ok for women that have had BC? ROMO
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Old 08-31-2006, 05:40 PM   #5
RobinP
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Check the ASCO 2006 website. There's a recent study there that says HRT tx. in bc patients does not increase relapse. Of course, you want to make sure that you have a hormonal negative bc. Most her2+s are er/pr negative.
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Old 08-31-2006, 08:38 PM   #6
snoopy
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??? STAR Trial

Might be straying off the point somewhat but ?? is your friend thinking of the STAR trial???

Compared Tamoxifen with Raloxifene (currently indicated to prevent/treatpostmenopausal osteoporosis) in the PREVENTION of BC

http://www.cancer.gov/newscenter/pre...sultsApr172006

Don't know if there are published/ongoing studies to the role of Raloxifene in BC patients
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Old 09-04-2006, 06:46 PM   #7
al from Canada
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treatments

Recent research has shown that taking calcium alone or with vitamin D does not increase bone density in post-menopausal women. Only a drugs such as actonel, fozamax or raloxifene actually increase bone density. As well, HRT has been shown to increase bone density.
http://www.docguide.com/news/content...256D8E006B421E
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Al
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Old 09-04-2006, 06:48 PM   #8
al from Canada
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....and more specific to BC

http://www.abreastinthewest.ca/active2.cfm?Num=41
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