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Old 09-29-2011, 03:17 PM   #1
CourtneyL
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Join Date: Aug 2008
Location: San Francisco
Posts: 260
Chloroquine - Sounds promising!

Hi All - I recently read this article in Cure magazine talking about the common anti-malarial drug, Chloroquine, as a potential destroyer of cancer stem cells. It all sounds very promising. There will soon be a multicenter clinical trail using it in triple negative bc:

http://curetoday.com/index.cfm/fusea...rticle_id/1749


Intrigued by the article, I did some further research and found some promising preliminary studies such as this one, discussing Chlroquine as a HER2 disruptor:

http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=40c77acf-0078-45fa-bd01-043689aa3ff6&cKey=6ca9e87b-b447-4fb2-9f67-60f3e7edb3bf&mKey={0591FA3B-AFEF-49D2-8E65-55F41EE8117E}

So should I plan a trip to Africa so I can get my Chloroquine prescription now? Why not? Its already FDA approved. I've got half a mind to just try this out myself. Does anyone have any experience with this or thoughts? I took this drug years ago when traveling through Central America and other than a few lucid dreams, it really didn't seem to have any negative side effects.
__________________
4/17/08: Dx Stage IV at age 30 - extensive mets to liver, lungs, and bones. Er/Pr-, Her2+++
April 08-Aug 08:Taxotere, Cytoxan, Herceptin, Zometa - complete response!
Sept 08-Dec 08: Herceptin +Zometa for maintenance.

Jan 09-April 09: Brain mets. Add Tykerb. Watch and wait.
April 09: Gamma Knife 10 brain mets, add Xeloda.
Sept 09: Gamma Knife to 1 brain met.
Nov 09- April 10: Lung progression, add Gemzar to Herceptin, Zometa.
May 10- Sept 10: HER2 Vaccine Trial

Sept 10: Add Tykerb for more brain mets.
Oct 10: Gamma Knife to 7 brain mets.
Dec 10: Switch from Zometa to Denosumab.
Jan 11: Gamma Knife to 3 brain mets.
March 11: Gemzar/Herceptin for lung/bone progression.
April 11: More brain mets - Intrathecal Herceptin
June 11: Ixempra/Herceptin for lung, soft tissue progression.
Aug 11: Gamma Knife
Sep 11: Abraxane/Herceptin
Future: NED

Send me a PM if you'd like to follow my journey on Caringbridge.
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