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Old 12-11-2007, 03:42 PM   #1
Margerie
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Extended therapy may benefit breast cancer patients

http://www.asco.org/portal/site/ASCO...reutersid=7581
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Dx 10/05 IDC, multi-focal, triple +, 5 nodes+
MRM, 4 DD A/C, 12 weekly taxol + herceptin
rads concurrent with taxol/herceptin
finished herceptin 01/08
ooph, Arimidex, bilateral DIEP reconstruction
NED
Univ. of WA, Seattle vaccine trial '07
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Old 12-11-2007, 10:29 PM   #2
sassy
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The report states:

"After approximately 5 years, the women who received anastrozole had a statistically significant 38 percent reduced risk of local and regional recurrence; cancer in the other breast; and distant spread of the disease, compared with women who received no further treatment.

However, there was no significant difference in overall survival between the treatment groups."

Can someone explain to me how these two statements relate? If there was a 38 percent reduced risk of recurrence, how could there be no significant difference in overall survival? If there is a decreased chance of recurrence, would this not increase survival?

Maybe I'm not looking at this correctly. Thanks to anyone who can help my muddled brain.
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Rhonda (Sassy)
dx age 45
DX 2/15/05 Stage IIb (at surgery)restaged IIIa
Left mast .9cm tumor 5 of 14 nodes
Triple Positive
4 DD A/C
12 Taxol/Herceptin
33Rads
Strange infect mast site one year aft surg, hosp 1 wk
Herceptin for total of 18 months
Lupron Monthly 4 yrs
Neurontin for aches, pains and hot flashes(It works!)
Ovaries removed 11/09 stop Lupron and Neurontin
Arimidex 6 yrs (tried Femara, no SE improvement)
Tried Exemestane-hips got so bad could hardly walk
Back to Arimidex for year seven
Zometa 2X Annual for 7years, Lasix
Stop Arimidex 5/13
Stop Zometa 7/13-Bi-lateral Stress Fractures in Femurs from Zometa
5/14 Start Tamoxifen
3/15 Stem cell transplant to stimulate femur bone growth/healing
5/15 Complete fracture of right femur/Titanium rods both femurs
9/16 Start Evista stopTamoxifen
3/17 Stop Evista--unwelcome side effects!
NED and no meds.......
14YEARS NED!
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