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Old 07-22-2010, 02:58 PM   #1
Dakini52
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Join Date: Jan 2010
Location: Edmonds, WA
Posts: 202
Question Tykerb Allergy

I have been on a combination of Herceptin and Tykerb for 6 months and recently developed an apparent allergy to Tykerb which caused severe swelling of uvela and throat along with a dry cough. My doctor has temporarily taken me off Tykerb while determining if I should continue. Has anyone else had this type of problem and if so what did you do?
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Old 07-22-2010, 09:06 PM   #2
vlcarr
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Posts: 343
Re: Tykerb Allergy

I was only on Tykerb/Hercp for 3 months and did not have this problem. I did develop mouth sores and would sometimes feel as if I had a hard time swallowing.

Wishing you the very best outcome.
__________________
Vicky
Age 47, TN, Diagnosed 05/09
Her2+, ER/PR-, Stage III, 2 tumors = 1 8cm tumor
Grade 3
Sentinel Node Biopsy-speck present in 1 node
Completed 3 month clinical trial of weekly Herceptin and 1000mg Tykerb daily
Tumor no longer present
Right mastectomy and lymph node removal 09/25/09
No cancer present at time of surgery, none in lymph nodes
Start TCH 10/15, every 3 weeks for 4 months followed by radiation
Finished chemo 01/28/10-YEAH!
Herceptin every 3 wks until end of June
Radiation begins 03/01, 6 1/2 weeks
Radiation complete--Yeah!!
Developed lymphedema after radiation
In hospital for 4 days with pneumonia:(
Herceptin done! 06/24/10
Port Removed 07/08/10
Still in PT for lymphedema and mobility issues
DIEP Reconstruction 05/11
I can be changed by what happens to me, but I refuse to be reduced by it~~Maya Angelou
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Old 07-25-2010, 01:12 PM   #3
Sandra in GA
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Re: Tykerb Allergy

I took Tykerb and Herceptin for a full year and did not have that problem ~ only the diarrhea and bleeding and sore fingers and toes.
__________________
Diagnosed: 7/25/08 ~ age 63, no family history
Surgery: 8/14/08 Bilateral mastectomy; tumor left breast, node dissection; right prophylactic with expanders: 1/12/10 latisimuss dorsi flap on left side: 9/22/10 implants in
Pathology Report: ER/PR-; HER2+ (3+); Grade 3, StageIII; 3cm tumor plus 21/21 lymph nodes positive; 5cm DCIS
Chemo: A/C; Taxol/Herceptin/Tykerb; phase II study at Mayo adding Tykerb for early stage
Radiation: 25 rads
Vaccine: Walter Reed GP2/AE37 vaccine study ~ last booster 9/17/2012
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